Neostigmine versus fentanyl administration with ropivacaine by patient-controlled epidural analgesia for the management of labor pain
المؤلف
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 8، العدد 2 (30 يونيو/حزيران 2015)، ص ص. 211-216، 6ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2015-06-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim The aim of this study was to evaluate the use of epidural Neostigmine (4 mcg/ml) in patientcontrolled epidural anesthesia ( PCEA) in the management of labor pain.
Patients and methods This randomized double-blind controlled prospective study was designed to compare PCEA Ropivacaine 0.15%+Fentanyl 2 mcg/ml (F group) with PCEA Ropivacaine 0.15%+Neostigmine 4 mcg/ml (N group).
The study included 60 ASA I–II laboring mothers.
Pain, sedation, nausea, maternal vital signs, motor power, and fetal heart rate were evaluated every 5 min after epidural bolus for the fi rst 30 min, and then every 2 h until delivery.
The incidence of shivering was documented.
Apgar scores at 1 and 5 min were documented.
Results There were no differences in maternal and labor characteristics between groups.
Progress of labor and modes of delivery were the same (P = 0.47).
Pain scores were signifi cantly reduced 20 min after initiation of analgesia compared with baseline in both groups (P < 0.001) and did not differ between groups at any time during the study (P = 0.21–0.43).
Addition of Neostigmine reduced the mean hourly epidural dose of Ropivacaine by 11% compared with the Fentanyl group (P = 0.003).
There were no differences in maternal vital signs between groups.
The sedation score increased compared with baseline through the fi rst 20 min after initiation of analgesia in both groups (Fentanyl P = 0.043 – Neostigmine P = 0.04).
There was no signifi cant difference in sedation scores between groups at any time or compared with baseline (P = 0.23–0.46).
The incidence of nausea, shivering, pruritus, and motor block was similar in both groups.
Conclusion Neostigmine 4 mcg/ml can be used as a safe adjuvant with Ropivacaine 0.15% by PCEA for the management of labor pain.
Its analgesic properties are comparable to that of epidural Fentanyl.
It causes temporary sedation within the fi rst 20 min.
This sedation is comparable to that of Fentanyl.
Epidural low-dose Neostigmine infusion did not increase the risk for nausea during labor.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khalaf, Ahmad A.. 2015. Neostigmine versus fentanyl administration with ropivacaine by patient-controlled epidural analgesia for the management of labor pain. Ain Shams Journal of Anesthesiology،Vol. 8, no. 2, pp.211-216.
https://search.emarefa.net/detail/BIM-650109
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khalaf, Ahmad A.. Neostigmine versus fentanyl administration with ropivacaine by patient-controlled epidural analgesia for the management of labor pain. Ain Shams Journal of Anesthesiology Vol. 8, no. 2 (Apr. / Jun. 2015), pp.211-216.
https://search.emarefa.net/detail/BIM-650109
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khalaf, Ahmad A.. Neostigmine versus fentanyl administration with ropivacaine by patient-controlled epidural analgesia for the management of labor pain. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 2, pp.211-216.
https://search.emarefa.net/detail/BIM-650109
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 216
رقم السجل
BIM-650109
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر