Comparative study between nalbuphine and dexamethasone for prevention of epidural morphine-induced pruritus in lower abdominal surgery
المؤلف
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 6، العدد 3 (31 ديسمبر/كانون الأول 2013)، ص ص. 264-267، 4ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2013-12-31
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Epidural morphine is an effective analgesic technique for lower abdominal surgery, but pruritus is its most common side effect.
Nalbuphine is an agonist–antagonist opioid and effective in treating opioid-induced pruritus.
Dexamethasone is a corticosteroid with anti-inflammatory and antiallergic properties.
We compared the effectiveness of intramuscular dexamethasone and nalbuphine in the prevention of epidural morphine-induced pruritus after lower abdominal surgery.
Methods One hundred and fifty, American Society of Anesthesiologists physical status I or II, patients undergoing lower abdominal surgery with epidural anesthesia were assigned randomly to three groups.
Group A, group B, and group C received intramuscular normal saline (2 ml; n = 50), dexamethasone (8 mg/2 ml; n = 50), and nalbuphine (10 mg/2 ml; n =50), respectively, after skin closure.
The occurrence and severity of pruritus were assessed at 1, 4, 8, and 12 h after surgery.
Results Pruritus occurred less frequently in group C than group B (Po0.05).
At 4, 8 and 12 h postoperatively, the severity of pruritus was significantly different (Po0.05) and was significantly less in group C than group B in the intergroup comparison (Po0.05).
Conclusion Nalbuphine proved to be better than dexamethasone in the prevention of epidural morphine-induced pruritus in patients who underwent lower abdominal surgery.
Prophylactic intramuscular nalbuphine (10 mg) is effective in decreasing the incidence and severity of pruritus and does not affect analgesia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muhammad, Mahmud H.. 2013. Comparative study between nalbuphine and dexamethasone for prevention of epidural morphine-induced pruritus in lower abdominal surgery. Ain Shams Journal of Anesthesiology،Vol. 6, no. 3, pp.264-267.
https://search.emarefa.net/detail/BIM-650116
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muhammad, Mahmud H.. Comparative study between nalbuphine and dexamethasone for prevention of epidural morphine-induced pruritus in lower abdominal surgery. Ain Shams Journal of Anesthesiology Vol. 6, no. 3 (Sep. / Dec. 2013), pp.264-267.
https://search.emarefa.net/detail/BIM-650116
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muhammad, Mahmud H.. Comparative study between nalbuphine and dexamethasone for prevention of epidural morphine-induced pruritus in lower abdominal surgery. Ain Shams Journal of Anesthesiology. 2013. Vol. 6, no. 3, pp.264-267.
https://search.emarefa.net/detail/BIM-650116
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 267
رقم السجل
BIM-650116
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر