Caudal levobupivacaine-fentanyl achieves stress response attenuation and early extubation in pediatric cardiac surgery
المؤلفون المشاركون
Bunduq, Rasha S.
al-Tahir, Walid al-Hajj Musa
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 7، العدد 1 (30 إبريل/نيسان 2014)، ص ص. 12-18، 7ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2014-04-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Adequate postoperative analgesia coupled with stress response attenuation in children are vital parts of perioperative care.
The present study was carried out to evaluate the efficacy of caudal levobupivacaine and fentanyl combination on stress response, postoperative analgesia, and extubation in pediatric cardiac surgery.
Patients and methods Fifty patients, ASA II-III, 2–8 years old, undergoing elective cardiac surgical repair were allocated randomly to two groups: group L received 0.125% levobupivacaine at a volume of 1.8 ml/kg; whereas group LF received 0.125% levobupivacaine plus fentanyl 1 μg/kg up to a volume of 1.8 ml/kg.
Results Intraoperative fentanyl consumption was significantly low in group LF compared with group L [1.56 ± 0.64 vs.
2.76 ± 0.52 μg/kg in group LF and group L, respectively, 95% confident interval (CI) 0.862–1.538; P < 0.001].
Extubation time was significantly shorter in group LF 2.24 ± 0.87 h compared with group L (5.84 ± 1.07 h, 95% CI 2.94 − 4.25; P < 0.001).
The duration of postoperative analgesia following extubation was significantly longer in group LF 4.56 ± 0.96 h compared with group L (2.21 ± 0.73 h, 95% CI 2.99 − 1.89; P < 0.001).
The serum cortisol levels were significantly higher in group L than group LF at T2, after sternotomy (21.92 ± 8.39 vs.
13.40 ± 5.48 μg/dl; P < 0.001); T3, after termination of cardiopulmonary bypass (32.32 ± 6.82 vs.
20.82 ± 5.85 μg/dl; P < 0.001); and T5, at extubation (36.64 ± 9.97 vs.
25.84 ± 9.16 μg/dl; P < 0.01).
Blood glucose levels increased significantly relative to baseline in both groups, but the increase was significantly lower in group LF compared with group L.
Conclusion Caudal levobupivacaine–fentanyl is effective in pediatric cardiac surgery; it attenuates the stress response with concomitant stabilization of hemodynamics.
In addition, it provides adequate postoperative analgesia and early extubation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Tahir, Walid al-Hajj Musa& Bunduq, Rasha S.. 2014. Caudal levobupivacaine-fentanyl achieves stress response attenuation and early extubation in pediatric cardiac surgery. Ain Shams Journal of Anesthesiology،Vol. 7, no. 1, pp.12-18.
https://search.emarefa.net/detail/BIM-650383
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Tahir, Walid al-Hajj Musa& Bunduq, Rasha S.. Caudal levobupivacaine-fentanyl achieves stress response attenuation and early extubation in pediatric cardiac surgery. Ain Shams Journal of Anesthesiology Vol. 7, no. 1 (Jan. / Apr. 2014), pp.12-18.
https://search.emarefa.net/detail/BIM-650383
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Tahir, Walid al-Hajj Musa& Bunduq, Rasha S.. Caudal levobupivacaine-fentanyl achieves stress response attenuation and early extubation in pediatric cardiac surgery. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 1, pp.12-18.
https://search.emarefa.net/detail/BIM-650383
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 18
رقم السجل
BIM-650383
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر