Pre-emptive intravenous ketorolac analgesia does not alter the risk of bleeding after tonsillectomy in children
المؤلفون المشاركون
Abd al-Majid, Walid M.
Hisham, Sulayman F.
Fath Allah, Muhammad A.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 8، العدد 1 (31 مارس/آذار 2015)، ص ص. 43-49، 7ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2015-03-31
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background NSAIDs inhibit platelet aggregation and prolong bleeding time, which may augment the risk of postoperative bleeding.
We investigated the effects of pre-emptive analgesia with intravenous ketorolac on intraoperative and postoperative hemorrhage with pediatric tonsillectomy.
Patients and Methods A total of 147 children, aged 2–7 years, scheduled for tonsillectomy with or without adenoidectomy were randomized to receive a slow intravenous infusion of either ketorolac 1 mg/kg (ketorolac group, n = 74) or paracetamol 15 mg / kg (paracetamol group, n = 73) after induction of anesthesia.
Noninvasive hemoglobin was assessed preoperatively and several times after surgery.
Bleeding times were measured before and after surgery.
Intraoperative blood loss was estimated.
Intensity of postoperative pain was measured using an objective pain score.
The incidence and severity of post-tonsillectomy bleeding were recorded until the seventh postoperative day.
Results There was no statistically signifi cant difference in the estimated intraoperative blood loss between ketorolac and paracetamol groups (2.4 ± 1.1 vs.
2.1 ± 0.8 ml/kg, respectively; P = 0.061).
Bleeding time increased between preoperative and postoperative assessments in both groups, with signifi cant postoperative elevation in the ketorolac group (P = 0.001).
Both groups were comparable regarding the perioperative noninvasive hemoglobin measurements.
The overall incidence of post-tonsillectomy bleeding was 5.4%, with no statistically signifi cant difference between ketorolac and paracetamol groups [5 (6.75%) vs.
3 (4.1%) patients, respectively; P = 0.705].
Postoperative objective pain score were signifi cantly lower in the ketorolac group on postanesthesia care unit admission and at 1, 2, and 6 postoperative hours (P < 0.05).
Conclusion Pre-emptive ketorolac infusion during pediatric tonsillectomy provides superior postoperative analgesia with no effect on intraoperative or postoperative clinical bleeding.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abd al-Majid, Walid M.& Hisham, Sulayman F.& Fath Allah, Muhammad A.. 2015. Pre-emptive intravenous ketorolac analgesia does not alter the risk of bleeding after tonsillectomy in children. Ain Shams Journal of Anesthesiology،Vol. 8, no. 1, pp.43-49.
https://search.emarefa.net/detail/BIM-650521
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abd al-Majid, Walid M.…[et al.]. Pre-emptive intravenous ketorolac analgesia does not alter the risk of bleeding after tonsillectomy in children. Ain Shams Journal of Anesthesiology Vol. 8, no. 1 (Jan. / Mar. 2015), pp.43-49.
https://search.emarefa.net/detail/BIM-650521
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abd al-Majid, Walid M.& Hisham, Sulayman F.& Fath Allah, Muhammad A.. Pre-emptive intravenous ketorolac analgesia does not alter the risk of bleeding after tonsillectomy in children. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 1, pp.43-49.
https://search.emarefa.net/detail/BIM-650521
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 48-49
رقم السجل
BIM-650521
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر