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Norepinephrine versus ephedrine for the prevention of spinal anesthesia-induced hypotension in coronary artery disease patients undergoing knee arthroscopy
المؤلفون المشاركون
al-Fawi, Dalya M.
al-Jundi, Hana A.
al-Shafii, Muhammad M.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 8، العدد 3 (30 سبتمبر/أيلول 2015)، ص ص. 424-428، 5ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2015-09-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Spinal anesthesia, a popular technique used for lower limb surgery in coronary artery disease patients, could be associated with hypotension, which could be managed with colloids, vasopressor, ephedrine, or norepinephrine (NE).
Aim The aim of this study was to assess the effi cacy and safety of bolus administration of NE versus ephedrine for the maintenance of systolic blood pressure during spinal anesthesia in coronary artery disease patients undergoing knee arthroscopy.
Patients and methods A randomized, controlled, double-blinded study was carried out on 100 ASA II or III coronary artery disease patients undergoing knee arthroscopy.
The patients were divided into two groups of 50 patients each: the ephedrine group (group EPH) and the norepinephrine group (group NE).
When hypotension occurred, group EPH received 5 mg of ephedrine and group NE received 5 μg of NE.
Systolic blood pressure and heart rate were recorded at 0, 5, 10, 15, 30, and 60 min, and side effects of both drugs were also recorded.
Results Effi cacy was found in 20 (40%) patients of group EPH and in 40 (80%) patients of group NE.
The results were highly signifi cant (P < 0.0001).
Tachycardia was signifi cantly higher (P < 0.0001) in group EPH.
The incidence of hypotension, hypertension, and bradycardia was not signifi cantly different between the two groups.
Conclusion NE is more effective compared with ephedrine in the maintenance of systolic blood pressure with reduction in heart rate, which is useful in coronary artery disease patients undergoing knee arthroscopy under spinal anesthesia in whom tachycardia is undesirable.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Shafii, Muhammad M.& al-Jundi, Hana A.& al-Fawi, Dalya M.. 2015. Norepinephrine versus ephedrine for the prevention of spinal anesthesia-induced hypotension in coronary artery disease patients undergoing knee arthroscopy. Ain Shams Journal of Anesthesiology،Vol. 8, no. 3, pp.424-428.
https://search.emarefa.net/detail/BIM-650934
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Shafii, Muhammad M.…[et al.]. Norepinephrine versus ephedrine for the prevention of spinal anesthesia-induced hypotension in coronary artery disease patients undergoing knee arthroscopy. Ain Shams Journal of Anesthesiology Vol. 8, no. 3 (Jul. / Sep. 2015), pp.424-428.
https://search.emarefa.net/detail/BIM-650934
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Shafii, Muhammad M.& al-Jundi, Hana A.& al-Fawi, Dalya M.. Norepinephrine versus ephedrine for the prevention of spinal anesthesia-induced hypotension in coronary artery disease patients undergoing knee arthroscopy. Ain Shams Journal of Anesthesiology. 2015. Vol. 8, no. 3, pp.424-428.
https://search.emarefa.net/detail/BIM-650934
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 427-428
رقم السجل
BIM-650934
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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