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Efficacy of lignocaine versus midazolam in controlling etomidate-induced myoclonus : a randomizedplacebo-controlled
المؤلفون المشاركون
Singh, Kahlon A.
Ruchi, Gupta
Singh, Aujla K.
Kaur, Bindra T.
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 7، العدد 3 (31 ديسمبر/كانون الأول 2014)، ص ص. 460-464، 5ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2014-12-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Background Etomidate has many desirable properties like rapid onset of profound hypnosis, short duration, hemodynamic stability, and minimal respiratory depression.
Few side effects such as myoclonus, reduced cortisol secretion, and pain on injection abate its regular use.
Aim The aim of this study was to evaluate the effect of pretreatment with lignocaine and midazolam on the incidence and severity of myoclonus due to etomidate.
Materials and methods A prospective, randomized, double-blind, placebo-controlled study was conducted on 75 patients with American Society of Anesthesiology physical status I or II, undergoing general anesthesia for various elective surgical procedures.
Patients were divided into three groups each comprising 25 patients: group I received 1 ml of normal saline, group II received 1 ml of 2% lignocaine and group III received 1 ml of midazolam (1 mg) as premedication 2 min before induction with 0.3 mg/kg etomidate.
Myoclonus was assessed and graded on a four-point scale.
Statistical data analysis Results were compiled and statistically analyzed using the χ2-test for nonparametric data and analysis of variance test for parametric data.
For all statistical analysis, P less than 0.05 was considered statistically signifi cant.
Results The incidence of myoclonus in control group was 76%, whereas patients premedicated with midazolam or lignocaine showed 28 and 44% incidence, respectively.
The severity of myoclonus was also decreased in both midazolam and lignocaine groups.
The incidence of other side effects among the groups was similar (P > 0.05).
Conclusion Premedication with both lignocaine and midazolam was effective in reducing the incidence and severity of myoclonus.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Singh, Kahlon A.& Ruchi, Gupta& Singh, Aujla K.& Kaur, Bindra T.. 2014. Efficacy of lignocaine versus midazolam in controlling etomidate-induced myoclonus : a randomizedplacebo-controlled. Ain Shams Journal of Anesthesiology،Vol. 7, no. 3, pp.460-464.
https://search.emarefa.net/detail/BIM-651771
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Singh, Kahlon A.…[et al.]. Efficacy of lignocaine versus midazolam in controlling etomidate-induced myoclonus : a randomizedplacebo-controlled. Ain Shams Journal of Anesthesiology Vol. 7, no. 3 (Sep. / Dec. 2014), pp.460-464.
https://search.emarefa.net/detail/BIM-651771
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Singh, Kahlon A.& Ruchi, Gupta& Singh, Aujla K.& Kaur, Bindra T.. Efficacy of lignocaine versus midazolam in controlling etomidate-induced myoclonus : a randomizedplacebo-controlled. Ain Shams Journal of Anesthesiology. 2014. Vol. 7, no. 3, pp.460-464.
https://search.emarefa.net/detail/BIM-651771
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 463-464
رقم السجل
BIM-651771
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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