The prevalence of thyroid dysfunction in patients with systemic lupus erythematosus
المؤلفون المشاركون
Rasaei, Nakisa
Nazarinia, Muhammad Ali
Shams, Misbah
Sarvestani, Iskandar Kamali
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 17، العدد 12 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
تاريخ النشر
2015-12-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease caused by immune system-mediated tissue damage.
Autoimmune thyroiditis (AT) is an organ-specific disease associated with production of a variety of antibodies such as antinuclear antibodies, anti-double-stranded DNA, anti-Ro antibodies and anti-cardiolipin antibodies.
Objectives : The aim of this study was to evaluate the prevalence of thyroid dysfunction and thyroid auto-antibodies in patients with SLE and its relation to SLE disease and other autoantibodies.
Patients and Methods : This was a case-control study.
The study included a total of 88 patients with SLE and 88 age- and sex-matched healthy volunteers as control group.
Two study groups were compared regarding thyroid function test, antinuclear antibody (ANA), antibodies to double-stranded DNA (dsDNA), anti- thyroglobulin antibody (anti-Tg), and anti-thyroid peroxidase (anti-TPO) antibody.
Results: The mean age of SLE patients and controls were 32.16 ± 9.19 and 32.48 ± 9.47 years, respectively (P = 0.821).
Patients had significantly higher prevalence (43.2 % vs.
23.9 %; P = 0.015) and titers (221.8 ± 570.5 vs.
78.2 ± 277.2; P = 0.036) of antibodies to Tg compared to controls.
The patients had significantly lower titers of T3 compared to controls (125.2 ± 35.6 vs.
136.2 ± 26.5; P = 0.021).
The titers of T4, TSH and anti-TPO antibody did not differ significantly between the two study groups.
Conclusions : Thyroid dysfunction was not higher in SLE patients compared to healthy individuals.
However, anti-Tg antibodies were higher in SLE patients.
It has not yet been established that thyroid function tests should be performed routinely in SLE patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rasaei, Nakisa& Shams, Misbah& Sarvestani, Iskandar Kamali& Nazarinia, Muhammad Ali. 2015. The prevalence of thyroid dysfunction in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal،Vol. 17, no. 12, pp.1-7.
https://search.emarefa.net/detail/BIM-652304
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rasaei, Nakisa…[et al.]. The prevalence of thyroid dysfunction in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal Vol. 17, no. 12 (Dec. 2015), pp.1-7.
https://search.emarefa.net/detail/BIM-652304
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rasaei, Nakisa& Shams, Misbah& Sarvestani, Iskandar Kamali& Nazarinia, Muhammad Ali. The prevalence of thyroid dysfunction in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal. 2015. Vol. 17, no. 12, pp.1-7.
https://search.emarefa.net/detail/BIM-652304
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6-7
رقم السجل
BIM-652304
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر