Effect of Artemisia judaica ethanolic extract on skin inflammation and hematological and biochemical characteristics of blood in rats

العناوين الأخرى

تأثير المستخلص الايثانولي لنبات البعيثران على الالتهابات الجلدية و الخصائص الدموية و البيوكيمائية للدم في الجرذان

مقدم أطروحة جامعية

Karjaghli, Darin Husayn

مشرف أطروحة جامعية

al-Shakanbah, Jumah Muti

أعضاء اللجنة

al-Shurafa, Khalid Yusuf Ahmad
Khulayfat, Khalid Muhammad
al-Laymun, Muhammad Awdah

الجامعة

جامعة مؤتة

الكلية

كلية العلوم

القسم الأكاديمي

قسم الأحياء

دولة الجامعة

الأردن

الدرجة العلمية

ماجستير

تاريخ الدرجة العلمية

2015

الملخص الإنجليزي

The effect of oral administration of ethanolic extract of the whole plant of Artemisia judaica on hematological and biochemical parameters were investigated in male albino rats.

This study was intended to evaluate the anti-inflammatory activity in carrageenan induced paw edema.

Rats were divided into two groups, control group and treated group.

The treated rats were orally given 270 mg/kg body weight of ethanolic extract of A.

judaica for 4 weeks.

For anti-inflammatory activity test, both groups were injected with 0.1 ml of 1% lambda carrageenan in saline , and the degree of paw edema was assessed.

The results of the present study showed a non significant (P>0.05) change in RBCs count, hematocrit, serum levels of cholesterol, aspartate aminotranferase (ASAT), alkaline phosphotase (ALP), creatine kinase (CK) and uric acid.

Other parameters including glucose, triglyceride and urea were significantly (P<0.05) decreased as compared to control rats.

However, serum alanine aminotransferase (ALAT) levels were significantly increased (P<0.05).

The present results showed that total WBCs count and hemoglobin percentage were significantly (P<0.05) increased as compared to control rats.

On the other hand the ethanolic extract of A.

judaica showed inhibition on carrageenan induced rat paw edema, the thickness was significantly (P<0.05) increased as compared to control paw (saline).

It is concluded that chronic treatment with ethanolic extract of A.

judaica induces significant changes in some hematological and biochemical parameters of the rat blood.

In addition the ethanolic extract of A.

judaica showed significantly anti-inflammatory activity in the rat skin.

التخصصات الرئيسية

الأحياء
النبات

الموضوعات

• الفسيولوجيا

عدد الصفحات

36

قائمة المحتويات

• APA
• MLA
• AMA

لغة النص

الإنجليزية

نوع البيانات

رسائل جامعية

رقم السجل

BIM-656389