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Value of cerebrospinal fluid tumor necrosis factor-alpha (TNF-alpha) for rapid diagnosis of bacterial meningitis
المؤلفون المشاركون
al-Jundi, Iman Muhammad
Allam, Inas Hasan
al-Baz, Husam S.
Ali, Hani al-Sayyid Muhammad
Muntasir, Iman Fawzi
Khalifah, Riham Ali Ahmad
المصدر
Journal of the Egyptian Society of Parasitology
العدد
المجلد 45، العدد 3 (31 ديسمبر/كانون الأول 2015)، ص ص. 655-662، 8ص.
الناشر
الجمعية المصرية لعلم الطفيليات
تاريخ النشر
2015-12-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Meningitis is common in tropical areas and also in Egypt and has a world-wide distribution This study evaluated the potential role of CSF TNF α in diagnosis and differential diagnosis of acute meningitis (bacterial versus aseptic meningitis).
This case-control study was conducted between Ain Shams University Tropical Medicine Department and Embaba Fever Hospital.
Fifty patients with suspected meningitis were recruited during from January 2014 to June 2014.
They were divided according to culture results into 2 groups : GI: 40 patients with acute bacterial meningitis (proved by CSF culture), G2: 10 patients matched according to age and sex with clinical sings of CNS infection but without laboratory evidence of bacterial origin, (Suspected cases, and negative culture).
Both groups were subjected to thorough history taking, full clinical examination, and laboratory investigations including CSF analysis & CSF TNF was measured by ELISA.
The results showed a highly significant difference between cases and control regarding CSF TNF (P = 0.00).
The criteria’s of diagnostic validity test was 100 % for all at cutoff ≥275ng / ml and ≤700ng/ml with 100 % specificity and sensitivity.
A significant correlation between CSF-TNF and each of ESR (P = 0.003) & CSF cells (P = 0.015), without significant correlation regarding other parameters (P > 0.05).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muntasir, Iman Fawzi& al-Jundi, Iman Muhammad& Allam, Inas Hasan& al-Baz, Husam S.& Khalifah, Riham Ali Ahmad& Ali, Hani al-Sayyid Muhammad. 2015. Value of cerebrospinal fluid tumor necrosis factor-alpha (TNF-alpha) for rapid diagnosis of bacterial meningitis. Journal of the Egyptian Society of Parasitology،Vol. 45, no. 3, pp.655-662.
https://search.emarefa.net/detail/BIM-669115
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ali, Hani al-Sayyid Muhammad…[et al.]. Value of cerebrospinal fluid tumor necrosis factor-alpha (TNF-alpha) for rapid diagnosis of bacterial meningitis. Journal of the Egyptian Society of Parasitology Vol. 45, no. 3 (Dec. 2015), pp.655-662.
https://search.emarefa.net/detail/BIM-669115
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muntasir, Iman Fawzi& al-Jundi, Iman Muhammad& Allam, Inas Hasan& al-Baz, Husam S.& Khalifah, Riham Ali Ahmad& Ali, Hani al-Sayyid Muhammad. Value of cerebrospinal fluid tumor necrosis factor-alpha (TNF-alpha) for rapid diagnosis of bacterial meningitis. Journal of the Egyptian Society of Parasitology. 2015. Vol. 45, no. 3, pp.655-662.
https://search.emarefa.net/detail/BIM-669115
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 661-662
رقم السجل
BIM-669115
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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