Serum magnesium level and vascular stiffness in children with chronic kidney disease on regular hemodialysis
المؤلفون المشاركون
Zahir, Manal Muhammad
Abd al-Salam, Raja
Sabur, Randah
Mursi, Amal Abd al-Alim
Jamal, Dina
Abd al-Salam, Manal
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 27، العدد 2 (30 إبريل/نيسان 2016)، ص ص. 233-240، 8ص.
الناشر
تاريخ النشر
2016-04-30
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Chronic kidney disease (CKD) patients have a high prevalence of vascular calcifications, and cardiovascular disease is the leading cause of death in this population.
Magnesium (Mg) depletion may be the missing link between multiple cardiovascular risk factors and the development of atherosclerosis.
In this study, we aimed to assess the relationship between serum Mg levels and vascular stiffness in children with CKD on regular hemodialysis (HD).
The study included 25 children with CKD on regular HD in our center; the study included also 25 healthy children age- and sex-matched as a control group.
Serum Mg levels were measured, and Doppler ultrasound assessment of the intima-media thickness (IMT) and the peak systolic velocities (PSVs) of the main arteries including the (aorta, carotid, and femoral) arteries were recorded in the study patients.
There were significantly lower serum Mg levels in children on regular HD than in the controls (1.7 ± 0.43 mg/dL vs.
2.31 ± 0.12 mg / dL, respectively, P = 0.001).
There was a significant increase in the aorta and carotid IMT in the study group than in the controls (0.45 ± 0.07 mm vs.
0.40 ± 0.09 mm; 0.98 ± 0.57 mm vs.
0.55 ± 0.1 mm, P = 0.034 and 0.001, respectively), whereas there were no significant differences regarding the PSV of the carotid, aorta, and femoral arteries between the study patients and the controls (P > 0.05).
A negative correlation was found between serum Mg level with aortic IMT (AIMT) (r = −0.682; P = 0.000).
In addition, a significant negative correlation was found between the AIMT with systolic and diastolic blood pressure (r = 0.447, P = 0.025, 0.472, P = 0.017), respectively.
We conclude that lower serum Mg levels were associated with vascular calcification in chronic HD children.
Confirmation of our results warrants further study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zahir, Manal Muhammad& Abd al-Salam, Manal& Abd al-Salam, Raja& Sabur, Randah& Mursi, Amal Abd al-Alim& Jamal, Dina. 2016. Serum magnesium level and vascular stiffness in children with chronic kidney disease on regular hemodialysis. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 2, pp.233-240.
https://search.emarefa.net/detail/BIM-677891
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zahir, Manal Muhammad…[et al.]. Serum magnesium level and vascular stiffness in children with chronic kidney disease on regular hemodialysis. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 2 (Mar. / Apr. 2016), pp.233-240.
https://search.emarefa.net/detail/BIM-677891
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zahir, Manal Muhammad& Abd al-Salam, Manal& Abd al-Salam, Raja& Sabur, Randah& Mursi, Amal Abd al-Alim& Jamal, Dina. Serum magnesium level and vascular stiffness in children with chronic kidney disease on regular hemodialysis. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 2, pp.233-240.
https://search.emarefa.net/detail/BIM-677891
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 238-240
رقم السجل
BIM-677891
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر