Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation
المؤلفون المشاركون
Sunil, Rajan
Lakshmi, Kumar
Pillai, Sarath Vijayakrishna
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 9، العدد 1 (31 مارس/آذار 2016)، ص ص. 99-103، 5ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2016-03-31
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Nitrous oxide enhances the anesthetic potential of other agents and thereby reduces their requirement.
Aims This study aimed to determine the effect of nitrous oxide inhalation on the induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation.
Settings and design This was a randomized, prospective clinical trial.
Participants and methods A total of 150 surgical patients ASA status I and II were included in the study.
Patients in group A inhaled 66% nitrous oxide in oxygen for 3 min, whereas in group B, 100% oxygen was used.
In both the groups, patients were administered a propofol bolus 20 mg every minute intravenously after 3 min of gas inhalation until induction was achieved.
Loss of response to verbal command and no response to jaw thrust were considered the endpoint of induction.
Patients were then intubated after administration of suxamethonium 2 mg/kg.
Results The mean dose of propofol required for induction was signifi cantly lower in group A compared with group B (30.4 ± 26.17 vs.
101.87 ± 26.19), as was the induction time (1.52 ± 1.31 vs.
5.09 ± 1.33).
Heart rate was comparable throughout the study period.
At induction, group A had a signifi cantly highe r mean arterial pressure (MAP) (94.51 ± 16.21 vs.
86.57 ± 15.47).
At 5 and 10 min, MAP was signifi cantly high in group B and signifi cantly high oxygen saturation was observed at induction (99.81 ± 0.46 vs.
99.96 ± 0.26).
No patient developed desaturation (SpO2 < 90 %) during the study.
Conclusion Inhalation of 66 % nitrous oxide for 3 min signifi cantly reduced the induction time and the dose of propofol, prevented a precipitous decrease in MAP at induction, and effectively attenuated stress response to laryngoscopy and intubation without desaturation
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sunil, Rajan& Pillai, Sarath Vijayakrishna& Lakshmi, Kumar. 2016. Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation. Ain Shams Journal of Anesthesiology،Vol. 9, no. 1, pp.99-103.
https://search.emarefa.net/detail/BIM-679014
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sunil, Rajan…[et al.]. Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation. Ain Shams Journal of Anesthesiology Vol. 9, no. 1 (Jan. / Mar. 2016), pp.99-103.
https://search.emarefa.net/detail/BIM-679014
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sunil, Rajan& Pillai, Sarath Vijayakrishna& Lakshmi, Kumar. Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation. Ain Shams Journal of Anesthesiology. 2016. Vol. 9, no. 1, pp.99-103.
https://search.emarefa.net/detail/BIM-679014
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 102-103
رقم السجل
BIM-679014
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر