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Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation : a comparative evaluation
المؤلفون المشاركون
Gupta, Kumkum
Bansal, Manoranjan
Gupta, Prashant K.
Singh, Meetu
Agarwal, Shikha
Tiwari, Vaibhav
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 9، العدد 1 (31 مارس/آذار 2016)، ص ص. 66-71، 6ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2016-03-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Direct laryngoscopy and tracheal intubation predictably lead to transient and variable hemodynamic responses, which can be attenuated by 2-receptor agonists.
The present study aimed to evaluate comparatively the three different dosages of dexmedetomidine (0.5, 0.8, and 1 g / kg) as premedication for the attenuation of these hemodynamic responses of direct laryngoscopy and intubation.
Participants and methods Ninety adult consented patients of ASA grades I and II of either sex were randomized into three equal groups of 30 patients each in a double-blind manner.
Dexmedetomidine in dosages of 0.5 g / kg (group I), 0.8 g / kg (group II), and 1 g / kg (grou p III) was infused over 10 min as premedication before propofol induction.
The hemodynamic changes during infusion, after induction, and after laryngoscopy and intubation were recorded for statistical analysis.
Results Patients with a comparable demographic profi le showed a decrease in heart rate and blood pressure after dexmedetomidine infusion in a dose-dependent manner.
Further decrease in heart rate and blood pressure after propofol induction showed a statistically signifi cant (P < 0.05) difference among groups.
After laryngoscopy and intubation, the increase in heart rate and blood pressure was more evident in patients in whom low dosages of dexmedetomidine was infused with a statistically signifi cant (P < 0.05) difference among the groups.
Conclusion Premedication with dexmedetomidine at a dosage of 1 g / kg attenuated the adverse hemodynamic responses of laryngoscopy and intubation adequately.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gupta, Kumkum& Bansal, Manoranjan& Gupta, Prashant K.& Singh, Meetu& Agarwal, Shikha& Tiwari, Vaibhav. 2016. Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation : a comparative evaluation. Ain Shams Journal of Anesthesiology،Vol. 9, no. 1, pp.66-71.
https://search.emarefa.net/detail/BIM-679016
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gupta, Kumkum…[et al.]. Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation : a comparative evaluation. Ain Shams Journal of Anesthesiology Vol. 9, no. 1 (Jan. / Mar. 2016), pp.66-71.
https://search.emarefa.net/detail/BIM-679016
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gupta, Kumkum& Bansal, Manoranjan& Gupta, Prashant K.& Singh, Meetu& Agarwal, Shikha& Tiwari, Vaibhav. Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation : a comparative evaluation. Ain Shams Journal of Anesthesiology. 2016. Vol. 9, no. 1, pp.66-71.
https://search.emarefa.net/detail/BIM-679016
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 71
رقم السجل
BIM-679016
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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