The effects of dual and triple combinations of trandolapril, telmisartan, and verapamil on overt proteinuria in the patients with diabetic nephropathy
المؤلفون المشاركون
al-Bayraq, Bulent
Cankaya, Erdem
Cetinkaya, Ramadan
Bilen, Yusuf
Cerrah, Serkan
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 27، العدد 3 (30 يونيو/حزيران 2016)، ص ص. 512-518، 7ص.
الناشر
تاريخ النشر
2016-06-30
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Diabetic nephropathy (DN) is one of the most important causes of the end-stage renal failure and its prevalence is found to be increasing.
The presence of hypertension and progressive proteinuria is among the important findings.
In this study, the effects of double and triple combinations of trandolapril, telmisartan, and verapamil on proteinuria were investigated in diabetic patients with nephropathy.
Seventy-eight patients (mean age: 56.11 ± 11.26 years; 47 females and 31 males) with overt proteinuria and DN were included in this study.
The patients were divided into four groups: Group I (n: 18, trandolapril + telmisartan), Group II (n: 20, trandolapril + verapamil), Group III (n: 20, trandolapril +telmisartan + verapamil), and Group IV (n: 20, telmisartan + verapamil).
At the end of a three-month therapy, within and between group comparisons were done about the effects of the use of double or triple drug combinations on proteinuria, glomerular filtration rate (GFR), electrolytes, serum albumin, low-density lipoprotein (LDL)- cholesterol, and HbA1C.
There was no significant difference among groups in terms of age, gender, diabetes duration, body mass index, and retinopathy frequency.
The decreases in proteinuria and mean arterial blood pressure (MABP) were significant in all groups.
The decrease in proteinuria was independent of the decrease in MABP [the reduction rate in proteinuria was 39% (P <0.001) in Group I, 37% (P <0.001) in Group II, 42% (P <0.001) in Group III, and 43% (P <0.001) in Group IV; the reduction rate in MABP was 10.6% (P <0.001) in Group I, 13.7% (P <0.001) in Group II, 17.5% (P <0.001) in Group III, and 15.4% (P <0.001) in Group IV].
Decrease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Bayraq, Bulent& Cankaya, Erdem& Cetinkaya, Ramadan& Cerrah, Serkan& Bilen, Yusuf. 2016. The effects of dual and triple combinations of trandolapril, telmisartan, and verapamil on overt proteinuria in the patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 3, pp.512-518.
https://search.emarefa.net/detail/BIM-683541
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Bayraq, Bulent…[et al.]. The effects of dual and triple combinations of trandolapril, telmisartan, and verapamil on overt proteinuria in the patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 3 (May. / Jun. 2016), pp.512-518.
https://search.emarefa.net/detail/BIM-683541
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Bayraq, Bulent& Cankaya, Erdem& Cetinkaya, Ramadan& Cerrah, Serkan& Bilen, Yusuf. The effects of dual and triple combinations of trandolapril, telmisartan, and verapamil on overt proteinuria in the patients with diabetic nephropathy. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 3, pp.512-518.
https://search.emarefa.net/detail/BIM-683541
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 518
رقم السجل
BIM-683541
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر