Baclofen-induced neurotoxicity in a patient with end-stage renal disease

الملخص EN

Baclofen, predominantly excreted by the kidneys is accumulated in patients with renal insufficiency leading to the central nervous system toxicity.

Here the author reports a patient with end-stage renal disease on maintenance hemodialysis (HD) who developed drowsiness and became unresponsive within a day after taking single 10 mg dose of baclofen.

Patient improved completely after two sessions of HD.