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Comparison of serum creatinine, cystatin c, and neutrophil gelatinase-associated lipocalin for acute kidney injury occurrence according to risk, injury, failure, loss, and end-stage criteria classification system in early after living kidney donation
المؤلفون المشاركون
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 27، العدد 4 (31 أغسطس/آب 2016)، ص ص. 659-664، 6ص.
الناشر
تاريخ النشر
2016-08-31
دولة النشر
السعودية
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
- الكلى
- وظائف الكلى
- الفحوصات الطبية
- زرع الأعضاء
- الليبوكالين
- الكرياتينين
- التبرعات
- الأعضاء البشرية
- مصل الدم
- الأنسجة
- الفشل الكلوي
- سيستاتين سي
- التشخيص
- الجوانب الجزيئية
الملخص EN
To evaluate the kidney function after living kidney donation, we measured serum creatinine (SCr), cystatin C, and neutrophil gelatinase-associated lipocalin (NGAL) of 42 living donors before uninephrectomy and in three immediate days after it.
We also evaluated the prevalence of the occurrence of the different stages of acute kidney injury (AKI) classified according to risk, injury, failure, loss, and end-stage (RIFLE) criteria, and accuracy of each of these three biomarkers for predicting them were evaluated.
Significant serum NGAL (s-NGAL) changes were limited to the 1st day after donation, whereas SCr and cystatin C changes continued to the third day after donation.
s-NGAL level in the 1st day and serum cystatin C in the 3rd day after donation, respectively, had the largest area under curve and best sensitivity and specificity for Stage 1 (risk) AKI prediction.
During the immediate three days after donation, about half of patients suffered from AKI; mostly Stage 1 (injury).
The sequence of the emergence of s-NGAL and s-cystatin C in the 1st and 3rd days as biomarkers with highest accuracy and power for RIFLE criteria defined AKI stage discrimination in our study was comparable to previous studies.
We conclude that our study suggests that AKI was best detected in the 1st day after uninephrectomy by the s-NGAL levels, whereas cystatin C was the best in the 3rd day after donation for detection of AKI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hikmat, Rida& Muhibi, Mahmud. 2016. Comparison of serum creatinine, cystatin c, and neutrophil gelatinase-associated lipocalin for acute kidney injury occurrence according to risk, injury, failure, loss, and end-stage criteria classification system in early after living kidney donation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 4, pp.659-664.
https://search.emarefa.net/detail/BIM-693013
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hikmat, Rida& Muhibi, Mahmud. Comparison of serum creatinine, cystatin c, and neutrophil gelatinase-associated lipocalin for acute kidney injury occurrence according to risk, injury, failure, loss, and end-stage criteria classification system in early after living kidney donation. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 4 (Jul. / Aug. 2016), pp.659-664.
https://search.emarefa.net/detail/BIM-693013
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hikmat, Rida& Muhibi, Mahmud. Comparison of serum creatinine, cystatin c, and neutrophil gelatinase-associated lipocalin for acute kidney injury occurrence according to risk, injury, failure, loss, and end-stage criteria classification system in early after living kidney donation. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 4, pp.659-664.
https://search.emarefa.net/detail/BIM-693013
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 663-664
رقم السجل
BIM-693013
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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