Germ cell tumors in undecided testis-prognostic factors and treatment outcome

المؤلفون المشاركون

al-Husayni, Jamal
Bazarbashi, Shawqi
al-Weshi, Amr
al-Fudah, Mahmud
Shawqi, Muhammad
Perracha, Amjad
Murad, Walid A.

المصدر

Journal of the Egyptian National Cancer Institute

العدد

المجلد 13، العدد 3 (30 سبتمبر/أيلول 2001)، ص ص. 209-214، 6ص.

الناشر

جامعة القاهرة المعهد القومي للأورام

تاريخ النشر

2001-09-30

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الموضوعات

الملخص EN

The medical records of 270 patients with germ cell tumors of the testis (147 seminoma and 123 non-seminoma) seen at our institute between 1975-1997 were reviewed.

Thirty-five (13 %) patients had tumors in undescended tes-tis ; seminoma in 28 and 7 patients had non-seminoma.

The mean age at diagnosis was 34 years.

Orchiopexy was performed in only 4 patients.

The involved testis was in the scrotum in the 4 patients who had orchiopexy, in the inguinal canal in 15 and in the lower abdomen in 16.

Pain and palpable mass were the most common presenting symptoms.

Using the modified Royal Marsden Hospital staging system, the stage at diagnosis was I in 14 patients, II in 18 and IV in 3.

Orchiectomy was carried out in 26 patients, open biopsy in 3 and fine needle aspiration in 6.

For patients with seminoma, 14 patients received external radiation (XRT) only, 7 chemotherapy, and combined XRT and chemotherapy in 6 patients.

One patient had orchiectomy only.

Patients with non-seminoma were treated with chemotherapy.

Complete response was achieved in 84 % of the seminoma cases.

At a median follow up of 52 months (range 2 months-19.5 years), the 5-year overall actuarial survival rate for patients with seminoma was 85 % compared to 68 % in patients with non-seminoma.

Univariate and multivariate analyses for survival were done for the 28 patients with seminoma.

Early stage and complete response to treatment were associated with significant high survival rate in univariate analysis.

None of the above were significant on multivariate analysis.

Conclusion : patients with undescended testes have a higher risk for developing seminoma than non-seminoma.

Treatment results of germ cell tumors in undescended tes-tis are equivalent to those in normally located testis.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

al-Husayni, Jamal& Shawqi, Muhammad& al-Weshi, Amr& al-Fudah, Mahmud& Bazarbashi, Shawqi& Perracha, Amjad…[et al.]. 2001. Germ cell tumors in undecided testis-prognostic factors and treatment outcome. Journal of the Egyptian National Cancer Institute،Vol. 13, no. 3, pp.209-214.
https://search.emarefa.net/detail/BIM-69326

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

al-Husayni, Jamal…[et al.]. Germ cell tumors in undecided testis-prognostic factors and treatment outcome. Journal of the Egyptian National Cancer Institute Vol. 13, no. 3 (Sep. 2001), pp.209-214.
https://search.emarefa.net/detail/BIM-69326

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

al-Husayni, Jamal& Shawqi, Muhammad& al-Weshi, Amr& al-Fudah, Mahmud& Bazarbashi, Shawqi& Perracha, Amjad…[et al.]. Germ cell tumors in undecided testis-prognostic factors and treatment outcome. Journal of the Egyptian National Cancer Institute. 2001. Vol. 13, no. 3, pp.209-214.
https://search.emarefa.net/detail/BIM-69326

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references : p. 213-214

رقم السجل

BIM-69326