Clostridium difficile associated diarrhea in pediatric oncology patients receiving chemotherapy
المؤلفون المشاركون
Ali al-Din, Nilli Hasan
al-Mahallawy, Haydar Ahmad
al-Hadda, Ala
Atiyyah, Iman A.
المصدر
Journal of the Egyptian National Cancer Institute
العدد
المجلد 13، العدد 4 (31 ديسمبر/كانون الأول 2001)، ص ص. 285-290، 6ص.
الناشر
جامعة القاهرة المعهد القومي للأورام
تاريخ النشر
2001-12-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background: Nowadays, patients with cancer receive more intensive chemotherapeutic regimens together with broad spectrum antibiotics during periods of profound immunosuppression.
Thus, cancer patients are susceptible to infection with clostridium difficile but the role of this pathogen in pediatric oncology patients is poorly defined.
Patients and methods: The prevalence of C.
difficile infection in pediatric oncology patients with diarrhea following chemotherapy was prospectively monitored, by testing for the presence of its A toxin, at National Cancer Institute, Cairo University.
Results: C.
difficile toxin A was detected in fifteen (14.4%) of 104 diarrhea episodes following chemotherapy.
Hospitalization, the use of antibiotics and relapsing disease were found to be significantly associated with this pathogen.
Two outbreaks were observed.
Severe enterocolitis with dehydration was significantly associated with C.
difficile than with other causes of diarrhea.
Case fatality rate directly attributable to C.
difficile infection was 20%.
Conclusion: C.
difficile is an important cause of diarrhea following intensive chemotherapeutic protocols and is associated with prolonged hospital stay and antibiotic use.
Moreover, C.
difficile have shown a strong association with morbidity and increased mortality and should be searched for as a cause of diarrhea in hospitalized pediatric cancer patients receiving empirical antibiotics
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Mahallawy, Haydar Ahmad& Ali al-Din, Nilli Hasan& Atiyyah, Iman A.& al-Hadda, Ala. 2001. Clostridium difficile associated diarrhea in pediatric oncology patients receiving chemotherapy. Journal of the Egyptian National Cancer Institute،Vol. 13, no. 4, pp.285-290.
https://search.emarefa.net/detail/BIM-69366
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Mahallawy, Haydar Ahmad…[et al.]. Clostridium difficile associated diarrhea in pediatric oncology patients receiving chemotherapy. Journal of the Egyptian National Cancer Institute Vol. 13, no. 4 (Dec. 2001), pp.285-290.
https://search.emarefa.net/detail/BIM-69366
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Mahallawy, Haydar Ahmad& Ali al-Din, Nilli Hasan& Atiyyah, Iman A.& al-Hadda, Ala. Clostridium difficile associated diarrhea in pediatric oncology patients receiving chemotherapy. Journal of the Egyptian National Cancer Institute. 2001. Vol. 13, no. 4, pp.285-290.
https://search.emarefa.net/detail/BIM-69366
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 290
رقم السجل
BIM-69366
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر