Comparison between the cassia fistula‘s emulsion with polyethylene glycol (PEG4000) in the pediatric functional constipation : a randomized clinical trial
المؤلفون المشاركون
Dooki, Muhammad Rida Ismaili
Mozaffarpur, Sayyid Ali
Mirzapour, Mohaddese
Shirafkan, Huda
Bijani, Ali
Kamalinejad, Muhammad
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 18، العدد 7 (31 يوليو/تموز 2016)، ص ص. 1-8، 8ص.
الناشر
تاريخ النشر
2016-07-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background : There are few effective drugs for pediatric functional constipation (FC).
Objectives : Comparing the effectiveness of Cassia fistula’s emulsion (CFE) with Polyethylene glycol (PEG4000) in FC; and evaluation of safety of both drugs in the treatment of FC.
Materials and Methods: A randomized open label, prospective, controlled, parallel-group clinical trial was carried on 109 children (M/F: 63/46; mean age SD: 59.7 28.8 months) in Amirkola children’s hospital, Babol, Iran.
The inclusion criteria were based on diagnosis of FC according to the Rome III criteria and age range between 2 - 15 years.
They received CFE or PEG randomly for 4 weeks.
Frequencies of defecation, severity of pain, consistency of stool, fecal incontinence and retentive posturing were compared between the two groups and with baselines.
Children were counted as improved when they exited from Rome III criteria of FC.
Results: Fifty seven patients were assigned to receive PEG and 52 patients received CFE.
After 4weeks of medication, 86.5 % of children in CFE group and 77.1 % in PEG group (RR = 1.121, CI95%:0.939 - 1.338) exited from the criteria of FC.
All measurable criteria improved in both groups without any significant difference, except in the frequency of defecation that in CFE group (10.965.7)wassignificantly more than PEG group (6.9 3.5) (P < 0.0001).
Compliances of PEG were significantly better in the 2 first weeks (P = 0.002, 0.008) but not in third and fourth week (P = 0.061, 0.062).
None of these two drugs cause clinically significant side effects.
Conclusions : CFE can be as effective as PEG in the 4-weeks treatment of children with FC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dooki, Muhammad Rida Ismaili& Mozaffarpur, Sayyid Ali& Mirzapour, Mohaddese& Bijani, Ali& Shirafkan, Huda& Kamalinejad, Muhammad. 2016. Comparison between the cassia fistula‘s emulsion with polyethylene glycol (PEG4000) in the pediatric functional constipation : a randomized clinical trial. Iranian Red Crescent Medical Journal،Vol. 18, no. 7, pp.1-8.
https://search.emarefa.net/detail/BIM-701494
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dooki, Muhammad Rida Ismaili…[et al.]. Comparison between the cassia fistula‘s emulsion with polyethylene glycol (PEG4000) in the pediatric functional constipation : a randomized clinical trial. Iranian Red Crescent Medical Journal Vol. 18, no. 7 (Jul. 2016), pp.1-8.
https://search.emarefa.net/detail/BIM-701494
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dooki, Muhammad Rida Ismaili& Mozaffarpur, Sayyid Ali& Mirzapour, Mohaddese& Bijani, Ali& Shirafkan, Huda& Kamalinejad, Muhammad. Comparison between the cassia fistula‘s emulsion with polyethylene glycol (PEG4000) in the pediatric functional constipation : a randomized clinical trial. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 7, pp.1-8.
https://search.emarefa.net/detail/BIM-701494
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 7-8
رقم السجل
BIM-701494
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر