Comparative study between general anesthesia and sciatic-femoral-obturator blockade as regards analgesia and incidence of postoperative cognitive dysfunction in elderly patients undergoing unilateral total knee replacement
المؤلفون المشاركون
Bhattacharya, Dipasri
Paul, Swarup
Naskar, Somnath
Mitrad, Manasij
Mandal, Mohanchandra
المصدر
Ain Shams Journal of Anesthesiology
العدد
المجلد 9، العدد 3 (30 سبتمبر/أيلول 2016)، ص ص. 387-392، 6ص.
الناشر
جامعة عين شمس كلية الطب قسم التخدير
تاريخ النشر
2016-09-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Postdural puncture headache (PDPH) is a very distressing symptom after spinal anesthesia.
It usually resolves spontaneously but may extend the length of hospital stay.
Although there are different measures to reduce the incidence, most of the times, none of them are effective.
Paracetamol is commonly used for the treatment of PDPH.
Pregabalin is recently being used for PDPH with effective results.
In this study, our aim was to compare the respective effects of paracetamol, pregabalin, and their combination in the treatment of PDPH.
Patients and methods In total, 150 patients who had undergone major gynecological surgery under spinal anesthesia and subsequently developed PDPH (diagnosed by postdural components of the pain) were randomly allocated by using computer-generated random numbers placed in sealed opaque envelopes.
The patients were allocated into three equal groups (n = 50, each group) to receive orally either a single dose of 150 mg pregabalin (group 1) or 1000 mg of paracetamol (group 2) or a combined dose of paracetamol 1000 mg plus pregabalin 150 mg (group 3).
All the patients received the same drug that they had originally received, if required, and were then followed up for 4 days.
A patient’s headache was scored using the visual analogue scale.
Results Earlier relief from PDPH and favorable adverse event profile (overall and central nervous system-related) were found in for the pregabalin–paracetamol combination compared with either of the drugs being used alone (P < 0.05).
Conclusion It was concluded that the pregabalin–paracetamol combination is a better option for the treatment of PDPH compared with both of the drugs when used alone.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bhattacharya, Dipasri& Paul, Swarup& Naskar, Somnath& Mitrad, Manasij& Mandal, Mohanchandra. 2016. Comparative study between general anesthesia and sciatic-femoral-obturator blockade as regards analgesia and incidence of postoperative cognitive dysfunction in elderly patients undergoing unilateral total knee replacement. Ain Shams Journal of Anesthesiology،Vol. 9, no. 3, pp.387-392.
https://search.emarefa.net/detail/BIM-709974
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bhattacharya, Dipasri…[et al.]. Comparative study between general anesthesia and sciatic-femoral-obturator blockade as regards analgesia and incidence of postoperative cognitive dysfunction in elderly patients undergoing unilateral total knee replacement. Ain Shams Journal of Anesthesiology Vol. 9, no. 3 (Jul. / Sep. 2016), pp.387-392.
https://search.emarefa.net/detail/BIM-709974
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bhattacharya, Dipasri& Paul, Swarup& Naskar, Somnath& Mitrad, Manasij& Mandal, Mohanchandra. Comparative study between general anesthesia and sciatic-femoral-obturator blockade as regards analgesia and incidence of postoperative cognitive dysfunction in elderly patients undergoing unilateral total knee replacement. Ain Shams Journal of Anesthesiology. 2016. Vol. 9, no. 3, pp.387-392.
https://search.emarefa.net/detail/BIM-709974
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 381-382
رقم السجل
BIM-709974
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر