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Clinical features and histological patterns of lupus nephritis in a single center of South India
المؤلفون المشاركون
Devadass, Clement Wilfred
Mysorekar, Vijaya Viswanath
Mekala, Lakshminarayanan
Siddaiah, M. Gireesh
Channabasappa, K. Gurudev
Eshwarappa, Mahesh
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 27، العدد 6 (31 ديسمبر/كانون الأول 2016)، ص ص. 1224-1230، 7ص.
الناشر
تاريخ النشر
2016-12-31
دولة النشر
السعودية
عدد الصفحات
7
التخصصات الرئيسية
الموضوعات
الملخص EN
Renal involvement occurs in up to 60 % of patients with systemic lupus erythe- matosus (SLE) and signifies a poor prognosis.
The class of lupus nephritis (LN), determined on renal biopsy evaluation, guides the therapeutic management and has prognostic connotations.
Our aim is to determine the clinicolaboratory features and histopathological patterns of LN at presentation in our local (South Indian) population.
The study was conducted in a tertiary care hospital in South India between 2009 and 2014 on SLE patients with clinical evidence of LN.
The renal biopsies were examined by light and immunofluorescence microscopy and were classified according to the International Society of Nephrology/Renal Pathology Society Classification of LN.
A total of 46 patients were included, with age range of 12–60 years and a female to male ratio of 8.2:1.
Arthritis, dermatological manifestations, and fever occurred, respectively, in 43.5%, 39.1%, and 30.4% of the cases.
Class IV LN was present in 17 (37.1%), Class III LN in ten (21.7%), Class II LN in nine (19.5 %), Class V LN in eight (17.4 %), Class I LN in one (2.2%), and Class VI LN in one (2.2 %) patients.
Antinuclear antibody (ANA) and dsDNA positivity were present, respectively, in 82.6% and 65.2 % of the patients.
The most common pattern of LN was Class IV LN followed by Class III LN.
Relatively higher proportions of ANA and anti-dsDNA positivity were present in proliferative LN, and there was a high frequency of arthritis at presentation in our LN patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Devadass, Clement Wilfred& Mysorekar, Vijaya Viswanath& Eshwarappa, Mahesh& Mekala, Lakshminarayanan& Siddaiah, M. Gireesh& Channabasappa, K. Gurudev. 2016. Clinical features and histological patterns of lupus nephritis in a single center of South India. Saudi Journal of Kidney Diseases and Transplantation،Vol. 27, no. 6, pp.1224-1230.
https://search.emarefa.net/detail/BIM-717280
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Devadass, Clement Wilfred…[et al.]. Clinical features and histological patterns of lupus nephritis in a single center of South India. Saudi Journal of Kidney Diseases and Transplantation Vol. 27, no. 6 (Nov. / Dec. 2016), pp.1224-1230.
https://search.emarefa.net/detail/BIM-717280
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Devadass, Clement Wilfred& Mysorekar, Vijaya Viswanath& Eshwarappa, Mahesh& Mekala, Lakshminarayanan& Siddaiah, M. Gireesh& Channabasappa, K. Gurudev. Clinical features and histological patterns of lupus nephritis in a single center of South India. Saudi Journal of Kidney Diseases and Transplantation. 2016. Vol. 27, no. 6, pp.1224-1230.
https://search.emarefa.net/detail/BIM-717280
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1230
رقم السجل
BIM-717280
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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