Grape seed extract supplementation and the effects on the biomarkers of oxidative stress and metabolic profiles in female volleyball players : a randomized, double-blind, placebo-controlled clinical trial
المؤلفون المشاركون
Memarzadeh, Muhammad Rida
Asemi, Zatollah
Taghizadeh, Muhsin
Malekian, Elaheh
Muhammadi, Ali Akbar
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 18، العدد 9 (30 سبتمبر/أيلول 2016)، ص ص. 1-9، 9ص.
الناشر
تاريخ النشر
2016-09-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background : Only limited data are available for evaluating the effects of the administration of grape seed extract (GSE) on the metabolic status of female volleyball players.
Objectives : This study was conducted to determine the effects of GSE administration on the metabolic status of female volleyball players.
Methods : This randomized, double-blind, placebo-controlled clinical trial was performed among 40 female volleyball players.
The subjects were randomly divided into two groups, with members of the test group (n = 20) taking 300mgof GSE twice a day for eight weeks and members of the control group (n = 20) taking a placebo pearl for the same period.
Fasting blood samples were taken before and after the eight-week intervention period in order to determine the related variables.
Results: Supplementation with GSE resulted in a significant rise in the plasma glutathione (GSH) level (+265.5 344.2 vs.
+2.2 378.2 mol/L, P = 0.02), as well as a significant decrease in the malondialdehyde (MDA) level (-1.4 2.0 vs.
-0.2 1.2 mol/L, P = 0.01) when compared to the placebo group.
In addition, when compared to the group that received the placebo, the subjects who received GSE had significantly decreased serum insulin concentrations (-23.4 23.4 vs.
+1.8 25.2 pmol / L, P = 0.002), a decreased homeostasis model of assessment for insulin resistance (HOMA-IR) (-0.70.7 vs.
+0.20.9, P = 0.002), and an increased quantitative insulin sensitivity check index (QUICKI) (+0.01 0.01 vs.
-0.01 0.02, P = 0.03).
The administration of GSE had no significant effects on creatine phosphokinase (CPK), total antioxidant capacity (TAC), nitric oxide (NO), fasting plasma glucose (FPG), and lipid concentrations when compared with the administration of the placebo.
However, after controlling for baseline NO levels, age, and baseline BMI, the changes in the plasma NO concentrations were significantly different between the two groups.
Conclusions : In conclusion, taking GSE for eight weeks had beneficial effects on the plasma GSH,MDAlevels, and markers of insulin metabolism of female volleyball players.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Taghizadeh, Muhsin& Malekian, Elaheh& Memarzadeh, Muhammad Rida& Muhammadi, Ali Akbar& Asemi, Zatollah. 2016. Grape seed extract supplementation and the effects on the biomarkers of oxidative stress and metabolic profiles in female volleyball players : a randomized, double-blind, placebo-controlled clinical trial. Iranian Red Crescent Medical Journal،Vol. 18, no. 9, pp.1-9.
https://search.emarefa.net/detail/BIM-724961
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Taghizadeh, Muhsin…[et al.]. Grape seed extract supplementation and the effects on the biomarkers of oxidative stress and metabolic profiles in female volleyball players : a randomized, double-blind, placebo-controlled clinical trial. Iranian Red Crescent Medical Journal Vol. 18, no. 9 (Sep. 2016), pp.1-9.
https://search.emarefa.net/detail/BIM-724961
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Taghizadeh, Muhsin& Malekian, Elaheh& Memarzadeh, Muhammad Rida& Muhammadi, Ali Akbar& Asemi, Zatollah. Grape seed extract supplementation and the effects on the biomarkers of oxidative stress and metabolic profiles in female volleyball players : a randomized, double-blind, placebo-controlled clinical trial. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 9, pp.1-9.
https://search.emarefa.net/detail/BIM-724961
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 8-9
رقم السجل
BIM-724961
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر