Drug reaction with eosinophilia and systemic symptoms induced by valproic acid : a case report
المؤلفون المشاركون
Darban, Mahbubah
Bagheri, Bahador
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 18، العدد 9 (30 سبتمبر/أيلول 2016)، ص ص. 1-5، 5ص.
الناشر
تاريخ النشر
2016-09-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction : Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but life-threatening reaction to drugs such as carbamazepine and allopurinol.
The condition is characterized by skin rashes, fever, hematological disturbances, lymphadenopathy, and organ failure, most probably hepatic dysfunction.
To date, only a few cases of valproate-induced DRESS syndrome have been reported.
Case Presentation : We report on the case of a 60-year-old man who had been treated with valproic acid some time before being referred to Kowsar Hospital, Semnan, Iran in December 2015.
He was given valproic acid 1000 mg PO, and after 20 days, he had developed widespread rashes, fever, esophagitis, cervical lymphadenopathy, and tender hepatomegaly.
Laboratory results at Kowsar showed a drop in hemoglobin, in addition to lymphocytosis, thrombocytopenia, and elevated serum transaminases.
DRESS was diagnosed, and corticosteroid therapy was initiated.
Administration of the culprit drug to the patient was also stopped.
Intravenous immunoglobulin (IVIG) improved the general condition of the patient.
Conclusions : Only a small number of case reports have described valproic acid-induced DRESS syndrome; therefore, the condition is difficult to prevent.
Rechallenge with valproic acid should be avoided in patients with a history of reaction to the drug.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Darban, Mahbubah& Bagheri, Bahador. 2016. Drug reaction with eosinophilia and systemic symptoms induced by valproic acid : a case report. Iranian Red Crescent Medical Journal،Vol. 18, no. 9, pp.1-5.
https://search.emarefa.net/detail/BIM-724971
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Darban, Mahbubah& Bagheri, Bahador. Drug reaction with eosinophilia and systemic symptoms induced by valproic acid : a case report. Iranian Red Crescent Medical Journal Vol. 18, no. 9 (Sep. 2016), pp.1-5.
https://search.emarefa.net/detail/BIM-724971
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Darban, Mahbubah& Bagheri, Bahador. Drug reaction with eosinophilia and systemic symptoms induced by valproic acid : a case report. Iranian Red Crescent Medical Journal. 2016. Vol. 18, no. 9, pp.1-5.
https://search.emarefa.net/detail/BIM-724971
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5
رقم السجل
BIM-724971
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر