Vitamin D and its binding protein in children with cystic fibrosis : a single center study
المؤلفون المشاركون
Shahin, Wala Abd al-Qasim
Hamid, Dina Husam al-Din
Al-Inbabi, Nifin Abdal-Munim
Sharaf, Sahar Abd al-Ati
Mahmud, Rihab Abd al-Khidr
Al-Falaqi, Muna Mustafa
المصدر
Egyptian Pediatric Association Gazette
العدد
المجلد 64، العدد 3 (30 سبتمبر/أيلول 2016)، ص ص. 131-135، 5ص.
الناشر
تاريخ النشر
2016-09-30
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aim : To measure the level of VDBP (vitamin D binding protein) and serum 25-hydroxy vitamin D (25OHD) in order to assess its role as a nutritional marker in cystic fibrosis (CF).
The relationship between vitamin DBP and immunoglobulin G (IgG) levels was assessed as well.
Methods : This is a cross-sectional observational study recruiting 50 patients diagnosed as having CF from the Allergy and Pulmonology Unit, Children’s Hospital, Cairo University, from May 2012 until May 2013, twenty age- and sex-matched healthy children were included as a control group.
Vitamin DBP and 25OHD were measured using Elisa technique and total IgG was measured using the nephelometer method.
Results : The CF group had significantly lower serum concentrations of DBP (p < 0.012) and 25OHD (p < 0.001) while IgG levels were within normal values (p < 0.216) compared to the control group, patients with failure to thrive (FTT) have significantly lower levels of 25OHD and significantly higher levels of VDBP and nearly the same level of IgG.
Patients with pancreatic insufficiency have significantly higher serum levels of VDBP.
Conclusions : The present study has demonstrated that the levels of 25OHD and VDBP are decreased in CF patients while IgG levels are within normal values.
In addition, the serum level of 25OHD was significantly lower in patients with FTT, also significant relations of VDBP with failure to thrive and pancreatic insufficiency were noted, emphasizing its role as a marker for the nutritional status in CF patients.
As a component of anti-inflammatory and nutritional therapy, vitamin D is a predictor for clinical outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shahin, Wala Abd al-Qasim& Hamid, Dina Husam al-Din& Al-Inbabi, Nifin Abdal-Munim& Sharaf, Sahar Abd al-Ati& Mahmud, Rihab Abd al-Khidr& Al-Falaqi, Muna Mustafa. 2016. Vitamin D and its binding protein in children with cystic fibrosis : a single center study. Egyptian Pediatric Association Gazette،Vol. 64, no. 3, pp.131-135.
https://search.emarefa.net/detail/BIM-726150
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shahin, Wala Abd al-Qasim…[et al.]. Vitamin D and its binding protein in children with cystic fibrosis : a single center study. Egyptian Pediatric Association Gazette Vol. 64, no. 3 (Sep. 2016), pp.131-135.
https://search.emarefa.net/detail/BIM-726150
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shahin, Wala Abd al-Qasim& Hamid, Dina Husam al-Din& Al-Inbabi, Nifin Abdal-Munim& Sharaf, Sahar Abd al-Ati& Mahmud, Rihab Abd al-Khidr& Al-Falaqi, Muna Mustafa. Vitamin D and its binding protein in children with cystic fibrosis : a single center study. Egyptian Pediatric Association Gazette. 2016. Vol. 64, no. 3, pp.131-135.
https://search.emarefa.net/detail/BIM-726150
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 135
رقم السجل
BIM-726150
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر