Staphylococcus aureus nasal carriage and obesity among patients with type two diabetes mellitus

الملخص EN

The study aimed to find an association between Type two diabetes mellitus (T2DM) patients, obesity and the rate of nasal carriage of Staphylococcus aureus (NCSA) producer of TSST-1 in patients with T2DM compared with non-diabetic control groups.

T2DM patients and control subjects were selected from outpatient of "The Specialist Center for Diseases of Endocrine and Diabetes" in Baghdad.

The subjects were divided into 4 groups : Group I included 21 obese T2DM patients; Group II included 20 lean T2DM patients; Group III included 20 obese as control group and Group IV included 21 lean as control group.

The study included sample with size (n = 82), male and female, with the ages ranged from 35 to 75 years, and the patients were not on any kind of anti-diabetic treatment.

A total number of the nasal carriage S.

aureus isolates were 38, of them 23 S.

aureus (56.1 %) were isolated from the groups of patients with T2DM and 15 Aureus isolates (38.46 %) were isolated from the control groups.

Molecular method was used to detect the presence of tstH gene in S.

aureus isolates indicating that the presence of toxic shock syndrome toxin-1.

The results revealed the presence of this gene in 12 (63.16%) S.

aureus isolates collected from T2DM patients and 7 (36.84 %) isolates collected from control groups