p53 : دوره في حراسة المحتوى المورثي و في الاستماتة الخلوية و كبح التسرطن : مراجعة في الأدب الطبي

الملخص EN

P53 is the guardian of genome from any alteration, its gene is called tumor suppressor gene .

p53 checks any alteration in cell cycle ,and if the alteration happened p53 resolves or shares in activation proteins important in resolving , if the cell couldn't resolve the alteration p53 leads it to apoptosis .

goingthe cell out of this nature cycle and continuing its resistance and proliferation makes it a tumor celland that make p53 very important study.