Nitrosylation of imidazo (1, 2-a)‎ pyridines in metal free system

الملخص EN

An efficient nitrosylation of imidazo[1,2-a]pyridines has been developed using tert-Butyl nitrite (TBN) as the NO resource.

The nitrosylation protocol demonstrates broad compatibilities, with various functional groups such as halogen, Me, OMe, COOMe et al.

well tolerated.

Near quantitative yields could be obtained within the imidazo[1,2-a]pyridine scaffold under the optimized conditions.