Autosomal dominant polycystic kidney disease : study of clinical characteristics in an Indian population
المؤلفون المشاركون
Vikrant, Sanjay
Parashar, Anupam
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 28، العدد 1 (28 فبراير/شباط 2017)، ص ص. 115-124، 10ص.
الناشر
تاريخ النشر
2017-02-28
دولة النشر
السعودية
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary form of kidney disease.
Clinical data on this multisystem disorder are scarce from developing countries.
We conducted a prospective observational study of the clinical profile of ADPKD patients at a single center over a period of six years.
A total of 208 patients were studied.
Majority were male (60.6%) and the mean age was 45.8 ± 14.5 years.
About 61.5% had early stage (Stages 1–3) of chronic kidney disease (CKD) and 38.5% had advanced CKD (Stages 4 and 5).
Clinical features observed included pain abdomen (46.2%), nocturia (65.9%), hematuria (21.6%), nephrolithiasis (38.9%), urinary tract infection (UTI) (38.9%), hypertension (69.5%), and raised serum creatinine (54.3%).
The prevalence of nocturia, hypertension, and renal dysfunction showed a significant increase with age (P = 0.001).
Extrarenal manifestations were polycystic liver disease in 77 patients (37%), cysts in pancreas in two (1%), and stroke in three (1.5%) (hemorrhage in 2 and infarct in 1).
There was significantly higher prevalence of hypertension (P = 0.027) and nephrolithiasis (P = 0.044) in males compared to females.
Ninety-two patients (44.2%) had a positive family history for ADPKD.
Fifteen (7.2%) had kidney failure at the diagnosis of ADPKD, were hospitalized, and underwent emergency dialysis.
A total of 20 patients (9.6%) developed end-stage kidney disease during the study period.
The age at diagnosis was higher, and there was a high prevalence of hypertension, nocturia, abdominal pain, nephrolithiasis, UTI, and renal dysfunction in Indian ADPKD patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vikrant, Sanjay& Parashar, Anupam. 2017. Autosomal dominant polycystic kidney disease : study of clinical characteristics in an Indian population. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 1, pp.115-124.
https://search.emarefa.net/detail/BIM-748882
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vikrant, Sanjay& Parashar, Anupam. Autosomal dominant polycystic kidney disease : study of clinical characteristics in an Indian population. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 1 (Jan. / Feb. 2017), pp.115-124.
https://search.emarefa.net/detail/BIM-748882
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vikrant, Sanjay& Parashar, Anupam. Autosomal dominant polycystic kidney disease : study of clinical characteristics in an Indian population. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 1, pp.115-124.
https://search.emarefa.net/detail/BIM-748882
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 123-124
رقم السجل
BIM-748882
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر