Study the toxic effect of different doses of Duprost in liver and blood of albino mice
العناوين الأخرى
دراسة التأثير السمي للجرع المختلفة من عقار Duprost في كبد و دم الفئران البيض
المؤلفون المشاركون
Muhammad, Ban Jasim
Muhammad, Duha Ibrahim
Yasin, Maha Salim
Ubayd, Hind Husayn
المصدر
العدد
المجلد 58، العدد 3B (30 سبتمبر/أيلول 2017)، ص ص. 1381-1392، 12ص.
الناشر
تاريخ النشر
2017-09-30
دولة النشر
العراق
عدد الصفحات
12
التخصصات الرئيسية
الموضوعات
الملخص EN
The aim of this study is to investigate the effect of different doses of Duprost in the liver and blood of albino mice.
The current study included twenty one albino mice, obtained and grouped into 3 groups: control (3 mice), acute group (12 mice) and chronic group (6 mice).
The acute group was subdivided into 4 groups and each group of 3mice, was given a lonely oral dose of (0.25ml, 0.15ml, 0.1 ml and 0.05ml respectively) for 24 hours.
Whereas the third group was subdivided into 2 groups and each set was given a daily dose of (0.15ml and 0.05 ml respectively) for 30 days.
After the mentioned periods, blood samples from each animal were taken for blood analysis.
Then, the mice of all groups were sacrificed and the livers were removed, processed, sectioned and stained for histological analysis.
In acute group, all mice that dosed with (0.25 ml) dose, died after 15 minutes of dosing.
Blood results showed significant decrease in Hb level, WBC's and platelets' count among acute subgroups in comparison with chronic subgroups which showed significant increase in WBC and platelets' count, but a significant decrease in Hb levels.
The histological analysis of liver in acute subgroups showed different forms of liver inflammation among acute subgroups, in comparison with chronic subgroups which showed formation of granulomatous lesions in the liver parenchyma in high dose(0.15ml) but there were inflammatory cells' aggregation in liver parenchyma among lower doses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muhammad, Ban Jasim& Ubayd, Hind Husayn& Muhammad, Duha Ibrahim& Yasin, Maha Salim. 2017. Study the toxic effect of different doses of Duprost in liver and blood of albino mice. Iraqi Journal of Science،Vol. 58, no. 3B, pp.1381-1392.
https://search.emarefa.net/detail/BIM-758611
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muhammad, Ban Jasim…[et al.]. Study the toxic effect of different doses of Duprost in liver and blood of albino mice. Iraqi Journal of Science Vol. 58, no. 3B (2017), pp.1381-1392.
https://search.emarefa.net/detail/BIM-758611
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muhammad, Ban Jasim& Ubayd, Hind Husayn& Muhammad, Duha Ibrahim& Yasin, Maha Salim. Study the toxic effect of different doses of Duprost in liver and blood of albino mice. Iraqi Journal of Science. 2017. Vol. 58, no. 3B, pp.1381-1392.
https://search.emarefa.net/detail/BIM-758611
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Text in English ; abstracts in English and Arabic.
رقم السجل
BIM-758611
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر