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Comparative investigation of thyroid autoantibodies between type 1 and type 2 diabetes mellitus patients in Baghdad City
العناوين الأخرى
دراسة مقارنة للأجسام المضادة للدرقية بين مرضى السكري من النوع الأول و الثاني في مدينة بغداد
المؤلف
al-Jawari, Suha Abd al-Khaliq Abd al-Sattar
المصدر
العدد
المجلد 58، العدد 2B (30 يونيو/حزيران 2017)، ص ص. 815-819، 5ص.
الناشر
تاريخ النشر
2017-06-30
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The level of thyroid autoantibodies between type 1 and type 2 diabetes mellitus patients in Baghdad City were investigated.
Fifty individuals (25 female and 25 male) with type-1 DM in the age group of 10 to 35 years and seventy (35 female and 35 male) of having type-2 DM in the age group of 33 to 60 years were investigated.
A control group of twenty-five non-diabetes was included.
Serum sample collected was used to estimate anti-TPO, TG and thyroid stimulating hormone antibodies (thyroid stimulating immunoglobulin TSI and thyrotropin binding inhibitory immunoglobulin TBII) by using enzyme-linked immunosorbent assay (ELISA) technique.
The results show that there is a significant (p< 0.05) increase in the level of thyroid peroxidase antibody (TPO-Ab) in female patients with T1DM and T2M compared with control non-diabetes group.
Furthermore, there is no significant (p< 0.05) difference in the level of TPO-Ab and Tg-Ab in male patients with T1DM and T2DM compared with non-diabetes group.
The results of this study also demonstrate that there is a significant (p< 0.05) increase in the level of thyroid stimulating immunoglobulin (TSI) in male patients with T1DM compared with control non-diabetes group.
In addition, there is no significant (p< 0.05) difference in the level of TSI in female patients with T1DM and male and female with T2DM compared with non-diabetes group.
These results also illustrate that there is significant (p< 0.05) increase in the level of thyrotropin binding inhibitory immunoglobulin (TBII) in female and male patients with T2DM compared with control non-diabetes group.
Furthermore, there is no significant (p< 0.05) difference in the level of TSI in female and male patients with T1DM compared with non-diabetes group.
From this study, it concluded that the presence of antithyroid peroxidase (TPO) antibodies is helpful in predicting the development of autoimmune thyroid disorders, especially hypothyroidism.
Subclinical hypothyroidism has a negative influence on lipid metabolism and it is an independent risk factor for myocardial infarction.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Jawari, Suha Abd al-Khaliq Abd al-Sattar. 2017. Comparative investigation of thyroid autoantibodies between type 1 and type 2 diabetes mellitus patients in Baghdad City. Iraqi Journal of Science،Vol. 58, no. 2B, pp.815-819.
https://search.emarefa.net/detail/BIM-761265
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Jawari, Suha Abd al-Khaliq Abd al-Sattar. Comparative investigation of thyroid autoantibodies between type 1 and type 2 diabetes mellitus patients in Baghdad City. Iraqi Journal of Science Vol. 58, no. 2B (2017), pp.815-819.
https://search.emarefa.net/detail/BIM-761265
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Jawari, Suha Abd al-Khaliq Abd al-Sattar. Comparative investigation of thyroid autoantibodies between type 1 and type 2 diabetes mellitus patients in Baghdad City. Iraqi Journal of Science. 2017. Vol. 58, no. 2B, pp.815-819.
https://search.emarefa.net/detail/BIM-761265
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 819
رقم السجل
BIM-761265
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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