Synthesis and characterization of new conjugated systems derived from piperazine-2,5-dione with antimicrobial screening

الملخص EN

The preparation of monoarylidene and unsymmetrical bisarylidene derivatives of 2,5- Piperazine dione is described.

The use of 1,4-diacetylpiperazine3,5-dione make it possible to prepare unsymmetrical bisarylidenes.

Antibacterial activity of the prepared new compounds against five types of bacteria were evaluated and the results showed that the new compounds exhibit good to moderate antibacterial activity.