Serologic evidence of exposure to west Nile virus among humans in Ibadan, southwestern Nigeria
المؤلفون المشاركون
Oluwayelu, Daniel Oladimeji
Sule, Waidi Folorunso
المصدر
Sudan Journal of Medical Sciences
العدد
المجلد 11، العدد 3 (30 سبتمبر/أيلول 2016)، ص ص. 111-124، 14ص.
الناشر
جامعة أم درمان الإسلامية كلية الطب
تاريخ النشر
2016-09-30
دولة النشر
السودان
عدد الصفحات
14
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : cases of fever without diagnoses of malaria and/or typhoid are usually regarded as undifferentiated febrile illness (UFI) in Nigeria.
We studied the contribution of WNV (an arbovirus) to UFI in humans in southwestern Nigeria.
Materials and methods : Sera from 188 consenting humans visiting two health care facilities in Ibadan, and 25 horse grooms from Lagos and Ibadan were screened for WNV antibodies by cELISA and a subset by PRNT.
Pertinent demographic/clinical data were collected and blood samples screened for Plasmodium spp, Salmonella typhi and S.
paratyphi antibodies.
Student’s t-test and binary logistic regression were used for data analysis.
Results : Overall, 156 participants (73.2%, 95% CI: 67.3-79.2 [n=213]) were positive for WNV antibodies.
Being clinically ill was associated (p=0.001) with WNV seropositivity while “active” and “non-active” participants had comparable (p=0.21) seroprevalence of 74.6% and 62.5%, respectively.
Forty-five percent (18/40) of febrile participants had WNV antibodies only, thereby accounting for UFI.
The 18-66 year olds had higher (75.8%) seroprevalence than those ? 17 years (47.4%) while seropositivity obtained for the horse grooms (56.0%) was significantly lower than for the remaining 188 individuals (75.5%).
Participants were mostly exposed to WNV (75.5%) than Plasmodium (33.5%) and S.
typhi (39.9%) while PRNT showed that 10.5% of tested humans had protective WNV antibodies.
Conclusions: This study revealed serologic evidence of exposure of the participants to WNV and contribution of the virus (or related flaviviruses) to UFI in the study area.
High prevalence of the antibodies indicates endemicity of southwestern Nigeria for WNV.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sule, Waidi Folorunso& Oluwayelu, Daniel Oladimeji. 2016. Serologic evidence of exposure to west Nile virus among humans in Ibadan, southwestern Nigeria. Sudan Journal of Medical Sciences،Vol. 11, no. 3, pp.111-124.
https://search.emarefa.net/detail/BIM-767983
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sule, Waidi Folorunso& Oluwayelu, Daniel Oladimeji. Serologic evidence of exposure to west Nile virus among humans in Ibadan, southwestern Nigeria. Sudan Journal of Medical Sciences Vol. 11, no. 3 (Sep. 2016), pp.111-124.
https://search.emarefa.net/detail/BIM-767983
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sule, Waidi Folorunso& Oluwayelu, Daniel Oladimeji. Serologic evidence of exposure to west Nile virus among humans in Ibadan, southwestern Nigeria. Sudan Journal of Medical Sciences. 2016. Vol. 11, no. 3, pp.111-124.
https://search.emarefa.net/detail/BIM-767983
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 122-124
رقم السجل
BIM-767983
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر