The effect of coumarin derivatives (compounds) on the Vibrio cholerae isolates from different clinical Iraqi sources
العناوين الأخرى
تأثير مركبات الكومارين على عزلات من بكتريا Vibrio cholera المعزولة من مصادر سريرية عراقية مختلفة
المؤلفون المشاركون
Abdul, Fatimah Ramadan
Tahir, Nihad Abd
Battah, Inam Hamid
Hasan, Ashraf Sami
المصدر
Iraqi Journal of Pharmaceutical Sciences
العدد
المجلد 26، العدد 1 (30 يونيو/حزيران 2017)، ص ص. 32-39، 8ص.
الناشر
تاريخ النشر
2017-06-30
دولة النشر
العراق
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
From a large number of bacterial samples collected from different hospital in Iraq in central health laboratory ,only ten isolates were identified primary as Vibrio.
A number of morphology and biochemical test were carried out to complete this identification that showed all bacterial isolates were related to Vibrio cholerae .In this study all Vibrio isolates were investigated for Bio typing and the result showed that all (10) isolate were related to (Eltor biotypes) .Also, the susceptibility test towards eight antibiotics were carried out .
Results shows that ciprofloxacin , Norfloxacin, Erythromycin, Ampicillin, ceftriaxone and Amikacin were the most effective antibiotics and their resistance percentage were 20%,20 %,20, 20,30% and 30% respectively ,While Chloramphenicol and Co- trimoxazole were less effective and their resistance percentage were 90 % both of them.
Three (3,5,6) isolates V.
cholerae were selected depending on results of antibiotics sensitivity tests as showed multiple –antibiotics resistance(100 %).
Then tested to study the effect of coumarin derivatives compounds (1, 2, 3 ) which showed inhibitory effect on V.
cholera (3,5,6) isolates and the compound ( 3 ) showed the highest antibacterial activity of (12,15,14 mm) of inhibition zone diameter against V.
cholera (3,5,6) isolates respectively.
Also, these Iraqi isolates (3,5,6) used to test the effect of acridine orange (0.1%) as acuring agent , the results showed that all (3) isolates V.
cholerae were sensitive to (ciprofloxacin, ceftrixone and Norfloxacin), While the rest were resistance to remained five antibiotics.
The results of Agarose –gel electrophoresis of both normal V.
cholerae (3,5,6) and cured isolates showed the presence of chromosomal and plasmid DNA bands in the normal case ,While only chromosomal DNA bands occur with V.
cholerae (isolate 8) treated with an acridine orange at concentration of (10-2 to 10-4).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdul, Fatimah Ramadan& Tahir, Nihad Abd& Hasan, Ashraf Sami& Battah, Inam Hamid. 2017. The effect of coumarin derivatives (compounds) on the Vibrio cholerae isolates from different clinical Iraqi sources. Iraqi Journal of Pharmaceutical Sciences،Vol. 26, no. 1, pp.32-39.
https://search.emarefa.net/detail/BIM-768891
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdul, Fatimah Ramadan…[et al.]. The effect of coumarin derivatives (compounds) on the Vibrio cholerae isolates from different clinical Iraqi sources. Iraqi Journal of Pharmaceutical Sciences Vol. 26, no. 1 (2017), pp.32-39.
https://search.emarefa.net/detail/BIM-768891
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdul, Fatimah Ramadan& Tahir, Nihad Abd& Hasan, Ashraf Sami& Battah, Inam Hamid. The effect of coumarin derivatives (compounds) on the Vibrio cholerae isolates from different clinical Iraqi sources. Iraqi Journal of Pharmaceutical Sciences. 2017. Vol. 26, no. 1, pp.32-39.
https://search.emarefa.net/detail/BIM-768891
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 37-39
رقم السجل
BIM-768891
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر