Computer assisted immunohistochemical score prediction via simplified image acquisition technique
المؤلفون المشاركون
Jawad, Salam N.
Abd Allah, Bashar H.
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 29، العدد 1 (31 مارس/آذار 2017)، ص ص. 83-88، 6ص.
الناشر
تاريخ النشر
2017-03-31
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الموضوعات
الملخص EN
Background : techniques of image analysis have been used extensively to minimize interobserver variation of immunohistochemical scoring, yet; image acquisition procedures are often demanding, expensive and laborious.
This study aims to assess the validity of image analysis to predict human observer’s score with a simplified image acquisition technique.
Materials and methods : formalin fixed- paraffin embedded tissue sections for ameloblastomas and basal cell carcinomas were immunohistochemically stained with monoclonal antibodies to MMP-2 and MMP-9.
The extent of antibody positivity was quantified using Imagej® based application on low power photomicrographs obtained with a conventional camera.
Results of the software were employed to predict human visual scoring results with stepwise multiple regression analysis.
Results : the overall prediction of epithelial score depicted as r square value was 0.26 (p<0.001) which was obviously higher than that of stromal score (0.10; p<0.01).
Epithelial and stromal MMP-2 score prediction was generally higher than that of MMP-9.
Collectively, ameloblastomas had a more efficient score prediction compared to basal cell carcinomas.
Conclusion : there is a considerable variability in the prediction capacity of the technique with respect to different antibodies, different tumors and cellular versus stromal score.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jawad, Salam N.& Abd Allah, Bashar H.. 2017. Computer assisted immunohistochemical score prediction via simplified image acquisition technique. Journal of Baghdad College of Dentistry،Vol. 29, no. 1, pp.83-88.
https://search.emarefa.net/detail/BIM-769988
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jawad, Salam N.& Abd Allah, Bashar H.. Computer assisted immunohistochemical score prediction via simplified image acquisition technique. Journal of Baghdad College of Dentistry Vol. 29, no. 1 (Mar. 2017), pp.83-88.
https://search.emarefa.net/detail/BIM-769988
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jawad, Salam N.& Abd Allah, Bashar H.. Computer assisted immunohistochemical score prediction via simplified image acquisition technique. Journal of Baghdad College of Dentistry. 2017. Vol. 29, no. 1, pp.83-88.
https://search.emarefa.net/detail/BIM-769988
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes appendices : p. 87-88
رقم السجل
BIM-769988
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر