Gestational diabetes mellitus and metabolic disorder among the different phenotypes of polycystic ovary syndrome
المؤلفون المشاركون
Ashrafi, Mahnaz
Sheikhan, Fatimah
Arabipoor, Arezoo
Rouhana, Nicole
Husayni, Ruya
Zolfaghari, Zahrah
المصدر
العدد
المجلد 32، العدد 3 (31 مايو/أيار 2017)، ص ص. 214-220، 7ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2017-05-31
دولة النشر
سلطنة عمان
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives: Polycystic ovary syndrome (PCOS) is a common endocrine disorder related to several metabolic consequences.
However, there remains uncertainty regarding the metabolic features of various phenotypes.
The aim of this study was to explore the relationship between the prevalence of gestational diabetes mellitus (GDM ) and metabolic disorders among the four different phenotypes of PCOS.
Methods: A crosssectional study was performed in Royan Institute including 208 pregnant women with a history of infertility and PCOS.
Using the diagnostic criteria of the American Diabetes Association (ADA ), pregnant women with a documented diagnoses of PCOS were further categorized into four different phenotypes (A, B, C, and D) as defined by the Rotterdam criteria.
Results: The prevalence of GDM failed to demonstrate a significant relationship among the four phenotypes of PCOS.
The mean levels of fasting blood sugar, plasma glucose concentrations at three hours (following the 100 g oral glucose tolerance test) and triglyceride levels were significantly higher in phenotype B compared to the remaining phenotypes (p < 0.050).
There was a statistically significant difference between the mean free testosterone level and phenotypes A and C groups (1.8±1.6 vs.
1.1±1.0, p = 0.003).
Conclusions: Women with a known diagnosis of PCOS who exhibited oligo/ anovulation and hyperandrogenism demonstrated an increase of metabolic disorders.
These results suggest that metabolic screening, before conception or in the early stages of pregnancy, can be beneficial particularly in women with PCOS phenotypes A and B.
Early screening and identification may justify enhanced maternal fetal surveillance to improve maternal and fetal morbidity among women affected with PCOS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ashrafi, Mahnaz& Sheikhan, Fatimah& Arabipoor, Arezoo& Rouhana, Nicole& Husayni, Ruya& Zolfaghari, Zahrah. 2017. Gestational diabetes mellitus and metabolic disorder among the different phenotypes of polycystic ovary syndrome. Oman Medical Journal،Vol. 32, no. 3, pp.214-220.
https://search.emarefa.net/detail/BIM-772337
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ashrafi, Mahnaz…[et al.]. Gestational diabetes mellitus and metabolic disorder among the different phenotypes of polycystic ovary syndrome. Oman Medical Journal Vol. 32, no. 3 (May. 2017), pp.214-220.
https://search.emarefa.net/detail/BIM-772337
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ashrafi, Mahnaz& Sheikhan, Fatimah& Arabipoor, Arezoo& Rouhana, Nicole& Husayni, Ruya& Zolfaghari, Zahrah. Gestational diabetes mellitus and metabolic disorder among the different phenotypes of polycystic ovary syndrome. Oman Medical Journal. 2017. Vol. 32, no. 3, pp.214-220.
https://search.emarefa.net/detail/BIM-772337
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 219-220
رقم السجل
BIM-772337
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر