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Utility of FNAC in conjunction with cell block for diagnosing space-occupying lesion (SOL) of liver with emphasis on differentiating hepatocellular carcinoma from metastatic SOL : analysis of 61 cases
المؤلفون المشاركون
Shifa, Haq
Lata, Jadhav
Basharat, Mubin
Rumana, Makhdumi
Veena, Malhotra
المصدر
العدد
المجلد 31، العدد 2 (31 مارس/آذار 2016)، ص ص. 135-141، 7ص.
الناشر
المجلس العماني للاختصاصات الطبية
تاريخ النشر
2016-03-31
دولة النشر
سلطنة عمان
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objectives : To study the cytological patterns of fine-needle aspiration cytology (FNAC) obtained from space-occupying lesions (SOLs) of the liver with an aim to differentiate primary hepatocellular carcinoma from metastatic deposits and to evaluate the added advantage and efficacy of studying cell blocks in conjunction with smears for enhancing diagnostic accuracy.
Methods: This prospective study took place over two years (September 2007 to 2009) and included 61 patients with cases of liver SOLs that were clinically or radiologically suspicious for malignancy and who were referred for computed tomography or ultrasonography-guided FNAC.
Smears were prepared from the aspirated material, and any remainder was used to make the cell block (n = 55).
A final diagnosis was made after evaluating the smears and cell block sections.
Results: On cytomorphology, a diagnosis of moderately differentiated hepatocellular carcinoma (HCC) and metastatic carcinoma was made in 10 (18.2%) and 25 (45.5%) cases, respectively, and were confirmed using cell block sections.
In cases where it was difficult to differentiate between welldifferentiated HCC and regenerative nodules, and between poorly differentiated HCC and poorly differentiated metastatic carcinoma, a final diagnosis was made with the help of cell blocks sections.
Cell blocks assisted in reaching a final diagnosis in 16 (29.1%) cases.
Cases that were diagnosed using cytomorphology were confirmed by the cell block method.
In these 39 (70.9%) cases we were able to render a diagnosis with much more confidence.
Conclusion: In our experience, difficulties in diagnosing SOL liver are attributed to differentiation of the tumor.
Cell block preparation gives an additional advantage as architectural details can be studied that help to reach an accurate diagnosis in problematic and challenging cases.
Thus, we strongly recommend the use of the cell block technique in conjunction with cytosmears for the purpose of diagnosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shifa, Haq& Lata, Jadhav& Basharat, Mubin& Rumana, Makhdumi& Veena, Malhotra. 2016. Utility of FNAC in conjunction with cell block for diagnosing space-occupying lesion (SOL) of liver with emphasis on differentiating hepatocellular carcinoma from metastatic SOL : analysis of 61 cases. Oman Medical Journal،Vol. 31, no. 2, pp.135-141.
https://search.emarefa.net/detail/BIM-772668
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shifa, Haq…[et al.]. Utility of FNAC in conjunction with cell block for diagnosing space-occupying lesion (SOL) of liver with emphasis on differentiating hepatocellular carcinoma from metastatic SOL : analysis of 61 cases. Oman Medical Journal Vol. 31, no. 2 (Mar. 2016), pp.135-141.
https://search.emarefa.net/detail/BIM-772668
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shifa, Haq& Lata, Jadhav& Basharat, Mubin& Rumana, Makhdumi& Veena, Malhotra. Utility of FNAC in conjunction with cell block for diagnosing space-occupying lesion (SOL) of liver with emphasis on differentiating hepatocellular carcinoma from metastatic SOL : analysis of 61 cases. Oman Medical Journal. 2016. Vol. 31, no. 2, pp.135-141.
https://search.emarefa.net/detail/BIM-772668
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 140-141
رقم السجل
BIM-772668
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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