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Assessment of hepatic fibrosis by Fibroscan in Egyptian chronic hemodialysis patients with chronic hepatitis C (genotype 4) : a single-center study
المؤلفون المشاركون
Zayid, Baha al-Din Mustafa
al-Sharqawi, Aishah
Abduh, Mahmud
Abd al-Fattah, Dina Sabri
al-Shabuni, Tariq Husayn
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 28، العدد 4 (31 أغسطس/آب 2017)، ص ص. 764-773، 10ص.
الناشر
تاريخ النشر
2017-08-31
دولة النشر
السعودية
عدد الصفحات
10
التخصصات الرئيسية
الموضوعات
الملخص EN
Assessing hepatic fibrosis in hemodialysis patients with chronic hepatitis C (CHC) can help to evaluate the long-term prognosis, complications of hepatitis C virus (HCV) as well as eligibility for renal transplantation,.
Our aim was to assess liver fibrosis in Egyptian hemodialysis (HD) patients infected with CHC genotype 4 using a fibroscan.
This crosssectional observational study was conducted over two years on a cohort of 134 Egyptian patients on prevalent HD at Kasr Al Ainy Hospital.
All patients were subjected to routine laboratory evaluation including, hepatitis B surface antigen, hepatitis B core antibody, hepatitis Be antigen, hepatitis C antibody (HCVAb) and human immunodeficiency virus antibody, quantitative polymerase chain reaction (PCR) for both HCV and hepatitis B virus (HBV), serum hyaluronic acid level, and alpha-fetoprotein (AFP).
Fibroscan was performed on all HCV-positive patients.
The mean age was 47.43 ± 12.65 years, 50.7% were male, and 49.3% were female.
The most common causes of end-stage renal disease were hypertensive nephropathy (32.1%) and diabetic nephropathy (18.7%).
HCVAb was positive in 57.5% of the patients and HBV was positive in 3%.
Forty HCV-positive patients (57.1%) who underwent fibroscan had mild to significant fibrosis, and thirty patients (42.9%) had advanced fibrosis.
There was significant correlation between HCV PCR and duration on HD, number of blood transfusions, and hyaluronic acid (HA) level.
In addition, there was a significant correlation between serum HA and HD duration as well as liver fibrosis.
No significant correlation was found between duration on HD and fibrosis stage (P = 0.619); also, no significant correlation was
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zayid, Baha al-Din Mustafa& al-Sharqawi, Aishah& Abduh, Mahmud& Abd al-Fattah, Dina Sabri& al-Shabuni, Tariq Husayn. 2017. Assessment of hepatic fibrosis by Fibroscan in Egyptian chronic hemodialysis patients with chronic hepatitis C (genotype 4) : a single-center study. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 4, pp.764-773.
https://search.emarefa.net/detail/BIM-776116
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zayid, Baha al-Din Mustafa…[et al.]. Assessment of hepatic fibrosis by Fibroscan in Egyptian chronic hemodialysis patients with chronic hepatitis C (genotype 4) : a single-center study. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 4 (Jul. / Aug. 2017), pp.764-773.
https://search.emarefa.net/detail/BIM-776116
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zayid, Baha al-Din Mustafa& al-Sharqawi, Aishah& Abduh, Mahmud& Abd al-Fattah, Dina Sabri& al-Shabuni, Tariq Husayn. Assessment of hepatic fibrosis by Fibroscan in Egyptian chronic hemodialysis patients with chronic hepatitis C (genotype 4) : a single-center study. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 4, pp.764-773.
https://search.emarefa.net/detail/BIM-776116
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 772-773
رقم السجل
BIM-776116
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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