Correlation of nuclear factor-KB, regulatory T cell and transforming growth factor B with rheumatoid arthritis
المؤلفون المشاركون
Sun, You
Zhao, De Li
Liu, Zi Xuan
Sun, Xue Hui
Li, Yang
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 24، العدد 8 (31 ديسمبر/كانون الأول 2017)، ص ص. 1849-1852، 4ص.
الناشر
تاريخ النشر
2017-12-31
دولة النشر
السعودية
عدد الصفحات
4
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الملخص EN
Objective : investigated the correlation of nuclear factor-jB, regulatory cells and transforming growth factor-b with rheumatoid arthritis.
Methods: Included 65 cases of RA patients admitted in our hospital from June 2015 to December 2016 into case group, and included 50 healthy people into control group during the same period.
Collected the peripheral detection of nuclear factor-jB, regulatory cells and transforming growth factor beta levels, and compared them between two groups.
Results : The percentage of CD4+, CD25+ T cells in the case group was significantly lower than that in the control group (P < .05) ; There was no significant difference in the percentage of CD4+, CD25+ CD127low/_, T cells between groups (P > .05); The levels of TGF - beta and NF - kappa B in the case group were higher than those in the control group, and the difference between the two groups was statistically significant (P < .05) ; The levels of ESR, CRP and RF in the case group were higher than those in the control group (P < .05).
There was a negative correlation between the expression of nuclear factor-jB, transforming growth factor-b and RF level in RA patients by pearson correlation analysis, r = _0.652, P < .05.
Conclusion: The expression levels of CD4+, CD25+ T cells in patients with RA are significantly decrease, which has a negative correlation with RA activity index RF, and showed that the pathogenesis of RA is related to the regulation of immune system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, You& Zhao, De Li& Liu, Zi Xuan& Sun, Xue Hui& Li, Yang. 2017. Correlation of nuclear factor-KB, regulatory T cell and transforming growth factor B with rheumatoid arthritis. Saudi Journal of Biological Sciences،Vol. 24, no. 8, pp.1849-1852.
https://search.emarefa.net/detail/BIM-780609
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, You…[et al.]. Correlation of nuclear factor-KB, regulatory T cell and transforming growth factor B with rheumatoid arthritis. Saudi Journal of Biological Sciences Vol. 24, no. 8 (Dec. 2017), pp.1849-1852.
https://search.emarefa.net/detail/BIM-780609
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, You& Zhao, De Li& Liu, Zi Xuan& Sun, Xue Hui& Li, Yang. Correlation of nuclear factor-KB, regulatory T cell and transforming growth factor B with rheumatoid arthritis. Saudi Journal of Biological Sciences. 2017. Vol. 24, no. 8, pp.1849-1852.
https://search.emarefa.net/detail/BIM-780609
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1852
رقم السجل
BIM-780609
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر