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Detection of plasmid-mediated quinolone resistance in clinical isolates of nterobacteriaceae strains in Hamadan, West of Iran
المؤلفون المشاركون
Majlisi, Amir
Kakhki, Rida Kamili
Mashuf, Rasul Yusuf
Roointan, Amir
Abazari, Malik
Najjad, Amir Sasan Muzaffari
Alikhani, Muhammad Yusuf
المصدر
Saudi Journal of Biological Sciences
العدد
المجلد 25، العدد 3 (31 مارس/آذار 2018)، ص ص. 426-430، 5ص.
الناشر
تاريخ النشر
2018-03-31
دولة النشر
السعودية
عدد الصفحات
5
التخصصات الرئيسية
الموضوعات
الملخص EN
Plasmid mediated quinolone resistance (PMQR) determinants have arisen as a significant concern in recent years.
The aim of this study was screening of resistant-clinical isolates to fluoroquinolone antibiotics and detection of qnr and aac(σ)-Ib-cr genes.
For this purpose we collected 100 fluoroquinolone-resistant Enterobacteriaceae which were from 3 hospitals in Hamadan, west provinces of Iran, between October 2012 and June 2013.
The all samples were identified by biochemical tests and confirmed by PCR method.
Antimicrobial susceptibility to 14 antimicrobial agents including levofloxacin and iprofloxacin were determined by disk diffusion methods and ciprofloxacin MIC was obtained by broth microdilution method as clinical laboratory standards institute (CLSI) recommendations.
The isolates were screened for the presence of qnrA, qnrB, qnrS and aac(σ)-Ib-cr genes using PCR assay.
Among the screened isolates, 64 strains (64 %) of Escherichia coli, 23 strains (23 %) of Klebsiella pneumoniae, 13 strains (13 %) of Proteus mirabilis were collected as quinolone-resistant isolates.
out of 100 isolates, two (2 %) were positive for qnrS, seventeen (17 %) isolates were positive for qnrB and we did not find qnrA gene in any of the isolates.
There were also 32 positive isolates for aac(σ)-Ib-cr determinant.
We described the prevalence of qnr and aac(σ)-Ib-cr genes in fluoroquinolone-resistant Enterobacteriaceae in Hamadan city.
The carriage rate of multidrug-resistant Enterobacteriaceae in healthy people in Hamadan city is extremely high.
Moreover, genes encoding transferable quinolones, in particular aac(σ)-Ibcr, are highly prevalent in these strains.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Majlisi, Amir& Kakhki, Rida Kamili& Najjad, Amir Sasan Muzaffari& Mashuf, Rasul Yusuf& Roointan, Amir& Abazari, Malik…[et al.]. 2018. Detection of plasmid-mediated quinolone resistance in clinical isolates of nterobacteriaceae strains in Hamadan, West of Iran. Saudi Journal of Biological Sciences،Vol. 25, no. 3, pp.426-430.
https://search.emarefa.net/detail/BIM-780701
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Majlisi, Amir…[et al.]. Detection of plasmid-mediated quinolone resistance in clinical isolates of nterobacteriaceae strains in Hamadan, West of Iran. Saudi Journal of Biological Sciences Vol. 25, no. 3 (Mar. 2018), pp.426-430.
https://search.emarefa.net/detail/BIM-780701
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Majlisi, Amir& Kakhki, Rida Kamili& Najjad, Amir Sasan Muzaffari& Mashuf, Rasul Yusuf& Roointan, Amir& Abazari, Malik…[et al.]. Detection of plasmid-mediated quinolone resistance in clinical isolates of nterobacteriaceae strains in Hamadan, West of Iran. Saudi Journal of Biological Sciences. 2018. Vol. 25, no. 3, pp.426-430.
https://search.emarefa.net/detail/BIM-780701
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 429-430
رقم السجل
BIM-780701
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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