Risk factors for acute coronary events in patients with rheumatoid arthritis
المؤلفون المشاركون
Nur Wali, Abd al-Salam
Umran, Narjis
al-Madini, Samah H.
al-Barbari, Amal M.
المصدر
Egyptian Rheumatology and Rehabilitation
العدد
المجلد 44، العدد 4 (31 ديسمبر/كانون الأول 2017)، ص ص. 164-171، 8ص.
الناشر
الجمعية المصرية للروماتيزم و التأهيل
تاريخ النشر
2017-12-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives The aim of this study was to assess the role of disease activity, line of treatment, and carotid atherosclerosis in the risk for acute coronary syndrome (ACS) in rheumatoid arthritis (RA) patients.
Patients and methods In this prospective study, we ascertained ACS on 124 patients with RA.
Disease activity score 28 was used for the assessment of RA activity.
Insulin resistance was evaluated using homeostasis model assessment-insulin resistance.
Carotid atherosclerosis was measured using high-resolution ultrasound.
We used Cox’s proportional hazards models to estimate the association between ACS and atherosclerosis, cardiovascular (CV) risk factors, and RA line of treatment.
Results Among the 124RApatients without a history of previousACS, 16 incidentACSevents occurred over 30 months.
Old age, long RA disease duration, high BMI, and 10-year cardiovascular disease risk were associated with an increased risk for ACS.
High mean disease activity score 28, rheumatoid factor, and anticitrullinated peptide antibodies (ACPA) levels were significantly associated with ACS risk.
Treatment with disease-modifying antirheumatic drugs or biological disease-modifying antirheumatic drugs (DMARDs) did not alter the ACS risk.
Logistic regression analysis showed that carotid plaques were a good predictor for ACS in RA patients.
Conclusion The main finding of this study was a general tendency toward an association of disease activity, rheumatoid factor, and ACPA with the risk for ACS.
In addition, subclinical atherosclerosis detected by means of carotid intima-media thickness and the presence of carotid plaques were good predictors for RA patients with ACS.
Treatment with any DMARD or biologic DMARDs was not linked to an altered risk for ACS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nur Wali, Abd al-Salam& Umran, Narjis& al-Madini, Samah H.& al-Barbari, Amal M.. 2017. Risk factors for acute coronary events in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation،Vol. 44, no. 4, pp.164-171.
https://search.emarefa.net/detail/BIM-783840
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nur Wali, Abd al-Salam…[et al.]. Risk factors for acute coronary events in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation Vol. 44, no. 4 (Oct. / Dec. 2017), pp.164-171.
https://search.emarefa.net/detail/BIM-783840
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nur Wali, Abd al-Salam& Umran, Narjis& al-Madini, Samah H.& al-Barbari, Amal M.. Risk factors for acute coronary events in patients with rheumatoid arthritis. Egyptian Rheumatology and Rehabilitation. 2017. Vol. 44, no. 4, pp.164-171.
https://search.emarefa.net/detail/BIM-783840
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 170-171
رقم السجل
BIM-783840
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر