Clinicopathological study of nondiabetic renal disease in type 2 diabetic patients : a single center experience from India
المؤلفون المشاركون
Nigam, Lovelesh
Vanikar, Aruna V.
Patel, Rashmi D.
Kanodia, Kamal V.
Suthar, Kamlesh S.
Patel, Himanshu
المصدر
Saudi Journal of Kidney Diseases and Transplantation
العدد
المجلد 28، العدد 6 (31 ديسمبر/كانون الأول 2017)، ص ص. 1330-1337، 8ص.
الناشر
تاريخ النشر
2017-12-31
دولة النشر
السعودية
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Diabetic nephropathy (DN) is a major complication of diabetes mellitus (DM), leading to chronic kidney disease/end-stage renal disease.
Wide spectrum of nondiabetic renal diseases (NDRD) is reported in type-2 diabetes (type-2 DM).
We carried out this single-center study to find clinical, laboratory, and histological features of NDRD in type-2 DM patients and to assess the prevalence of NDRD in India.
A single-center retrospective study which included analysis of renal biopsies from patients with type-2 DM, performed between January 2008 and September 2016.
Biopsy findings were categorized into three groups, Group-I (isolated NDRD); Group-II (NDRD superimposed on underlying DN); and Group-III (isolated DN).
Out of 152 diabetic patients (111 males and 41 females), 35 (23.03%) patients were of Group-I (isolated NDRD), 35 (23.03%) of Group-II (NDRD superimposed on underlying DN), and 82 (53.95%) of Group-III (isolated DN).
The mean age (in years) was 55.08 ± 10.71, 55.65 ± 8.71, and 54.45 ± 9.01 respectively in Group-I, II, and III.
Nephrotic syndrome (NS) was the most common clinical presentation in all groups.
Duration of DM was significantly shorter in Group-I than in Group-II.
Diabetic retinopathy was absent in Group-I.
Proteinuria was more in Group-III than Group-I.
Low serum C3 and/or C4 levels was observed in five (14.29%) cases of Group-I and Group-II each and two (2.43%) cases of Group-III.
Nearly, 70 (46.05%) patients were found to have NDRD either in isolated form or as combined lesions.
The most common histological types of NDRD were acute tubulointerstitial nephritis (38.57%) followed by benign nephrosclerosis (15.72%), membranous nephropathy (10%), IgA nephropathy (7.14%), and membranoproliferative glomerulonephritis (7.14%).
The incidence of NDRD (with/without DN) in type-2 DM is very high.
Shorter duration of diabetes, hematuria, absence of retinopathy, low serum complement levels, and nephrotic range proteinuria are predictors of NDRD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kanodia, Kamal V.& Vanikar, Aruna V.& Nigam, Lovelesh& Patel, Rashmi D.& Suthar, Kamlesh S.& Patel, Himanshu. 2017. Clinicopathological study of nondiabetic renal disease in type 2 diabetic patients : a single center experience from India. Saudi Journal of Kidney Diseases and Transplantation،Vol. 28, no. 6, pp.1330-1337.
https://search.emarefa.net/detail/BIM-785650
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kanodia, Kamal V.…[et al.]. Clinicopathological study of nondiabetic renal disease in type 2 diabetic patients : a single center experience from India. Saudi Journal of Kidney Diseases and Transplantation Vol. 28, no. 6 (Nov. / Dec. 2017), pp.1330-1337.
https://search.emarefa.net/detail/BIM-785650
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kanodia, Kamal V.& Vanikar, Aruna V.& Nigam, Lovelesh& Patel, Rashmi D.& Suthar, Kamlesh S.& Patel, Himanshu. Clinicopathological study of nondiabetic renal disease in type 2 diabetic patients : a single center experience from India. Saudi Journal of Kidney Diseases and Transplantation. 2017. Vol. 28, no. 6, pp.1330-1337.
https://search.emarefa.net/detail/BIM-785650
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 1336-1337
رقم السجل
BIM-785650
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر