Toxicity of Balanites aegyptiaca seeds oil in wistar albino rats
العناوين الأخرى
سمية زيت بذور الهجليج في الجرذان البيضاء
المؤلفون المشاركون
Jamil, Ahmad Abd al-Rahim
Muhammad, Abd al-Wahhab Hasan
al-Hasan, Jalal al-Din al-Azhari Muhammad
Ali, Sumayyah Awad al-Karim
المصدر
Journal of Science and Technology : in Agricultural and Veterinary Sciences
العدد
المجلد 18، العدد 1 (30 يونيو/حزيران 2017)، ص ص. 12-22، 11ص.
الناشر
جامعة السودان للعلوم و التكنولوجيا عمادة البحث العلمي
تاريخ النشر
2017-06-30
دولة النشر
السودان
عدد الصفحات
11
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الملخص EN
Balanites aegyptiaca (L.), a multipurpose tree, is used widely in the Sudan for its nutritional, cosmetic, industrial and medicinal values.
The seeds oil has been used by natives to treat rheumatism and as edible oil.
The present study was designed to investigate the toxicological status of B.
aegyptiaca seeds petroleum ether extract in Wistar albino rats in acute and sub-chronic toxicity models.
In acute toxicity model, rats were orally administered B.
aegyptiaca seeds petroleum ether extract at a dose of 2, 4, 8 and 20 ml/kg and observed for signs of toxicity and mortality for 24 hours.
In sub-chronic model, rats were given B.
aegyptiaca seeds oil at a dose of 4 and 8 ml/kg orally for 21 days.
Haematological parameters, liver and kidney function tests were taken before and after the administration of each treatment.
Histopathology was also performed for different organs.
The results indicated that no mortality was seen after administration of seeds oil up to 20 ml/kg in acute toxicity model.
On the other hand, oral administration of B.
aegyptiaca seeds petroleum ether extract for 21 days did not prove any signs of toxicity or organs damage as evidenced by insignificant (p> 0.05) change in haematological parameters, serum enzymes activities of ALT, AST, ALP, and urea and creatinine as well as total protein level in treated groups as compared with control group.
Furthermore, sections of different organs of treated animals showed minor insignificant histopathological changes, with exception of two kidney sections which showed focal degenerative changes in rats given high dose of extract.
In conclusion, the results of the present study indicated that the petroleum ether extract of B.
aegyptiaca seeds is safe when administered orally in rats in acute and sub-chronic toxicity models.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ali, Sumayyah Awad al-Karim& Muhammad, Abd al-Wahhab Hasan& al-Hasan, Jalal al-Din al-Azhari Muhammad& Jamil, Ahmad Abd al-Rahim. 2017. Toxicity of Balanites aegyptiaca seeds oil in wistar albino rats. Journal of Science and Technology : in Agricultural and Veterinary Sciences،Vol. 18, no. 1, pp.12-22.
https://search.emarefa.net/detail/BIM-790153
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ali, Sumayyah Awad al-Karim…[et al.]. Toxicity of Balanites aegyptiaca seeds oil in wistar albino rats. Journal of Science and Technology : in Agricultural and Veterinary Sciences Vol. 18, no. 1 (Jun. 2017), pp.12-22.
https://search.emarefa.net/detail/BIM-790153
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ali, Sumayyah Awad al-Karim& Muhammad, Abd al-Wahhab Hasan& al-Hasan, Jalal al-Din al-Azhari Muhammad& Jamil, Ahmad Abd al-Rahim. Toxicity of Balanites aegyptiaca seeds oil in wistar albino rats. Journal of Science and Technology : in Agricultural and Veterinary Sciences. 2017. Vol. 18, no. 1, pp.12-22.
https://search.emarefa.net/detail/BIM-790153
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 19-21
رقم السجل
BIM-790153
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر