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Oral health status, salivary MMP-8 and secretory leukocyte peptidase inhibitor (SLPI) among uncontrolled type-i diabetes mellitus in Iraqi patients
المؤلفون المشاركون
Ahmad, Rihab Faysal
al-Jabburi, Raja H.
المصدر
Journal of Baghdad College of Dentistry
العدد
المجلد 29، العدد 2 (30 يونيو/حزيران 2017)، ص ص. 65-70، 6ص.
الناشر
تاريخ النشر
2017-06-30
دولة النشر
العراق
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Back ground: diabetes is a metabolic disease characterized by hyperglycemia that results in deficiency or absence of insulin production.
The dental caries and gingivitis/periodontitis are widespread chronic diseases in diabetes.
The aim of the present study was determined the salivary matrix metalloproteinase (MMP-8), Secretory Leukocyte Peptidase Inhibitor (SLPI) and oral health status among uncontrolled diabetic group in comparison with healthy control group.
Materials and Methods: The total sample composed of 90 adults aged (18-35) years.
Divided into 60 uncontrolled diabetic patients (HbA1c >7%) and 30 healthy control group.
Unstimulated saliva was collected from each subject with type-I DM, BMI, duration of diabetes, HbA1c%, DMFT, gingival index (GI) and periodontal disease index were recorded during clinical visit.
Level of salivary MMP-8 and SLPI was measured by using ELISA immunoassay analysis.
Results: The DMFT was highly significant higher among type-I DM group than control group (p<0.001),GI and pocket depthwas significant difference (p=0.002, p<0.001 respectively) between two groups except the attachment loss with no significant difference (p=0.06).
The Salivary MMP-8 was elevated, whereas SLPI was lowered in individuals with type I diabetes mellitus in comparison to the healthy controls, but statistically was non-significant.
Analysis among uncontrolled diabetic patients revealed that the HbA1c% correlate positively significant with salivary MMP-8 (r=0.321, p=0.012), SLPI (r=0.276, P=0.033) andattachment loss (r=0.353, p=0.006); however the correlation between MMP-8 & SLPIwas a significant in negative direction (r=-0.395, p=0.002).
Conclusion:The DMFT, pocket depth and gingival index was higher in uncontrolled diabetes group.
HbA1c% was positively correlation withMMP-8, SLPI and attachment loss in uncontrolled diabetic group.
Salivary SLPI associated inversely with significant correlation with salivary MMP-8.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ahmad, Rihab Faysal& al-Jabburi, Raja H.. 2017. Oral health status, salivary MMP-8 and secretory leukocyte peptidase inhibitor (SLPI) among uncontrolled type-i diabetes mellitus in Iraqi patients. Journal of Baghdad College of Dentistry،Vol. 29, no. 2, pp.65-70.
https://search.emarefa.net/detail/BIM-792021
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ahmad, Rihab Faysal& al-Jabburi, Raja H.. Oral health status, salivary MMP-8 and secretory leukocyte peptidase inhibitor (SLPI) among uncontrolled type-i diabetes mellitus in Iraqi patients. Journal of Baghdad College of Dentistry Vol. 29, no. 2 (Jun. 2017), pp.65-70.
https://search.emarefa.net/detail/BIM-792021
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ahmad, Rihab Faysal& al-Jabburi, Raja H.. Oral health status, salivary MMP-8 and secretory leukocyte peptidase inhibitor (SLPI) among uncontrolled type-i diabetes mellitus in Iraqi patients. Journal of Baghdad College of Dentistry. 2017. Vol. 29, no. 2, pp.65-70.
https://search.emarefa.net/detail/BIM-792021
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 69-70
رقم السجل
BIM-792021
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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