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Emergence of blaoxa-carrying carbapenem resistance in multidrug-resistant acinetobacter baumannii in the intensive care unit
المؤلفون المشاركون
Moniri, Rezvan
Josheghani, Sarih Bagheri
Firuzah, Farzanih
Sihat, Mujtaba
Dastehgoli, Kamran
Kusha, Hasan
Farahani, Rida Khaltabadi
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 19، العدد 5 (31 مايو/أيار 2017)، ص ص. 1-7، 7ص.
الناشر
تاريخ النشر
2017-05-31
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
7
التخصصات الرئيسية
العلوم الطبية والصيدلة والعلوم الصحية
الملخص EN
Background: Emergence of multidrug-resistant (MDR) Acinetobacter baumannii infections is becoming a worldwide threat to hospitalized patients, particularly in intensive care units.
Objectives: The aim of this study was to investigate the antimicrobial susceptibility patterns and prevalence of blaOXA-type carbapenemases of A.
baumannii isolates in a teaching hospital in Iran.
Patients and Methods: The study included a total of 40 isolates of carbapenem-resistant A.
baumannii, obtained from 103 tracheal tubes in hospitalized ICU patients.
Antimicrobial susceptibility testing was performed according to CLSI guidelines.
The blaOXA-51, blaOXA-23, blaOXA-24, blaOXA-58, and ISAba1 genes were detected by PCR.
Results: All of the A.
baumannii isolates were resistant to imipenem and meropenem, and 100% of the isolates were MDR.
The blaOXA-51 and ISAba1 genes were detected in 100% of the isolates.
blaOXA-23 and blaOXA-24 were detected in 90% and 40% of the isolates, respectively, but blaOXA-58 was absent in the A.
baumannii isolates.
In addition, 32.5% of carbapenem-resistant strains contained at least three genes encoding blaOXA-type carbapenemase.
Colistin and polymyxin B were the most effective antibiotics.
The sole risk factor for infection of hospitalized patients with carbapenem-resistant Acinetobacter strains was age over 40 years (P = 0.042).
The mortality rate was 27.5%.
Conclusions: These findings signify the alarming spread of OXA genes inA.
baumannii strains in our intensive care unit.
The spread of carbapenem-resistant Acinetobacter strains has serious health implications and requires the application of strict infection-control measures.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Josheghani, Sarih Bagheri& Moniri, Rezvan& Firuzah, Farzanih& Sihat, Mujtaba& Dastehgoli, Kamran& Kusha, Hasan…[et al.]. 2017. Emergence of blaoxa-carrying carbapenem resistance in multidrug-resistant acinetobacter baumannii in the intensive care unit. Iranian Red Crescent Medical Journal،Vol. 19, no. 5, pp.1-7.
https://search.emarefa.net/detail/BIM-792055
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Josheghani, Sarih Bagheri…[et al.]. Emergence of blaoxa-carrying carbapenem resistance in multidrug-resistant acinetobacter baumannii in the intensive care unit. Iranian Red Crescent Medical Journal Vol. 19, no. 5 (May. 2017), pp.1-7.
https://search.emarefa.net/detail/BIM-792055
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Josheghani, Sarih Bagheri& Moniri, Rezvan& Firuzah, Farzanih& Sihat, Mujtaba& Dastehgoli, Kamran& Kusha, Hasan…[et al.]. Emergence of blaoxa-carrying carbapenem resistance in multidrug-resistant acinetobacter baumannii in the intensive care unit. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 5, pp.1-7.
https://search.emarefa.net/detail/BIM-792055
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 6-7
رقم السجل
BIM-792055
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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