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Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study
المؤلفون المشاركون
Rafraf, Maryam
Ghaffari, Ayidah
Navekar, Roya
Sepehri, Bita
Ghavami, Sayyid Mustafa
Munafi, Nahid
Asghari Jafarabadi, Muhammad
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 19، العدد 4 (30 إبريل/نيسان 2017)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2017-04-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Elevated levels of homocysteine (Hcy) and fetuin-A are important risk factors for cardiovascular diseases in patients with a nonalcoholic fatty liver disease (NAFLD).
There is limited evidence regarding the effects of turmeric on NAFLD.
Objectives: This study aimed at investigating the effects of turmeric supplementation on serum levels of Hcy and fetuin-A in patients with NAFLD.
Methods: In this double-blind, randomized, controlled clinical trial, 46 NAFLD patients (21 males and 25 females; age range, 20 - 60 years) with body mass index ranged 24.9 - 40 kg/m2 were recruited from Sheikh-ol-Raees clinic in Tabriz City, Iran during Nov 2014- May 2015.
The participants were allocated into the two groups using the block randomization method.
The intervention and control groups received 3g of turmeric (n = 23) and placebo (n = 23), daily for 12 weeks.
Fasting blood samples were collected at baseline and at the end of the trial for biochemical analysis.
Results: Turmeric supplementation significantly decreased serum levels of Hcy, compared with the placebo group at the end of the study (by 27.83%, P = 0.034).
No significant difference was observed between the two groups in serum levels of fetuin-A after the intervention (P > 0.05).
Serum levels of glucose, insulin and homeostasis model assessment for insulin resistance were declined significantly in the turmeric group (by 1.22%, 17.69% and 19.48%, P = 0.039, P = 0.013 and P = 0.001, respectively) compared to the placebo.
Conclusions: Turmeric consumption had beneficial effects on serum Hcy levels andmay be useful inmanagement of this risk factor in NAFLD patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghaffari, Ayidah& Rafraf, Maryam& Navekar, Roya& Sepehri, Bita& Asghari Jafarabadi, Muhammad& Ghavami, Sayyid Mustafa…[et al.]. 2017. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal،Vol. 19, no. 4, pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghaffari, Ayidah…[et al.]. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal Vol. 19, no. 4 (Apr. 2017), pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghaffari, Ayidah& Rafraf, Maryam& Navekar, Roya& Sepehri, Bita& Asghari Jafarabadi, Muhammad& Ghavami, Sayyid Mustafa…[et al.]. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 4, pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-796821
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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