Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study
المؤلفون المشاركون
Rafraf, Maryam
Ghaffari, Ayidah
Navekar, Roya
Sepehri, Bita
Ghavami, Sayyid Mustafa
Munafi, Nahid
Asghari Jafarabadi, Muhammad
المصدر
Iranian Red Crescent Medical Journal
العدد
المجلد 19، العدد 4 (30 إبريل/نيسان 2017)، ص ص. 1-6، 6ص.
الناشر
تاريخ النشر
2017-04-30
دولة النشر
الإمارات العربية المتحدة
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background: Elevated levels of homocysteine (Hcy) and fetuin-A are important risk factors for cardiovascular diseases in patients with a nonalcoholic fatty liver disease (NAFLD).
There is limited evidence regarding the effects of turmeric on NAFLD.
Objectives: This study aimed at investigating the effects of turmeric supplementation on serum levels of Hcy and fetuin-A in patients with NAFLD.
Methods: In this double-blind, randomized, controlled clinical trial, 46 NAFLD patients (21 males and 25 females; age range, 20 - 60 years) with body mass index ranged 24.9 - 40 kg/m2 were recruited from Sheikh-ol-Raees clinic in Tabriz City, Iran during Nov 2014- May 2015.
The participants were allocated into the two groups using the block randomization method.
The intervention and control groups received 3g of turmeric (n = 23) and placebo (n = 23), daily for 12 weeks.
Fasting blood samples were collected at baseline and at the end of the trial for biochemical analysis.
Results: Turmeric supplementation significantly decreased serum levels of Hcy, compared with the placebo group at the end of the study (by 27.83%, P = 0.034).
No significant difference was observed between the two groups in serum levels of fetuin-A after the intervention (P > 0.05).
Serum levels of glucose, insulin and homeostasis model assessment for insulin resistance were declined significantly in the turmeric group (by 1.22%, 17.69% and 19.48%, P = 0.039, P = 0.013 and P = 0.001, respectively) compared to the placebo.
Conclusions: Turmeric consumption had beneficial effects on serum Hcy levels andmay be useful inmanagement of this risk factor in NAFLD patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ghaffari, Ayidah& Rafraf, Maryam& Navekar, Roya& Sepehri, Bita& Asghari Jafarabadi, Muhammad& Ghavami, Sayyid Mustafa…[et al.]. 2017. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal،Vol. 19, no. 4, pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ghaffari, Ayidah…[et al.]. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal Vol. 19, no. 4 (Apr. 2017), pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ghaffari, Ayidah& Rafraf, Maryam& Navekar, Roya& Sepehri, Bita& Asghari Jafarabadi, Muhammad& Ghavami, Sayyid Mustafa…[et al.]. Effects of turmeric on homocysteine and fetuin-A in patients with nonalcoholic fatty liver disease : a randomized double-blind placebo-controlled study. Iranian Red Crescent Medical Journal. 2017. Vol. 19, no. 4, pp.1-6.
https://search.emarefa.net/detail/BIM-796821
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 5-6
رقم السجل
BIM-796821
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر