Humoral immune factor changes in group of patients with non-muscle invasive bladder cancer treated with intravesical therapy
المؤلفون المشاركون
Abd al-Karim, Muntaha
al-Dabbagh, Muhammad A. H.
Ata Allah, Muhammad L.
Hasan, Jabbar S.
المصدر
Journal of the Faculty of Medicine Baghdad
العدد
المجلد 59، العدد 4 (31 ديسمبر/كانون الأول 2017)، ص ص. 325-329، 5ص.
الناشر
تاريخ النشر
2017-12-31
دولة النشر
العراق
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background: Bladder cancer (BC) one of the most common urologic cancer characterized by the highest recurrence rate, many types belong to BC, but most common of them worldwide are transitional cell carcinoma(TCC) which constitute about 90-95% cases, squamous cell carcinoma (SCC) and adenocarcinomas Objective: This study was designed to evaluate parameters of humoral immunity in Non-muscle invasive (superficial or early) bladder cancer patients in Iraq that may provide a new insight into the future of immunotherapies development and BC management.
Materials and methods: Fifty-nine volunteer's patients ranged from 24 to 83years old, and 30 control individuals ranged from 51-80 years old, who attended and admitted to Hospital of Gazi AL-Harery in medical city of Baghdad, and Al-Emamain Al-Khadhemain Teaching hospital was recruited in this investigation.
The sera of study groups were subjected to serological test to estimate the levels of (IgA, IgG, IgM and C3) by Single radial immunodiffusion (sRID) assay and Enzyme-Linked immunosorbent assay (ELISA) was used to estimate the serum levels of IL-10.
Results: The ages ranged from 24 to 83years (females: 26 to 72years, males: 38 to 83years) with male to female ratio 4.9:1 and ages of controls ranged from 51 to 80years (females: 54 to 70years, males: 51 to 80years) with male to female ratio 2.75:1, the mean ages of cases and controls groups were (61.65±11.04) , current study showed significance dropping in C3 levels in patients control and Mitomycin C groups compared with apparently healthy, levels of IgM showed significant elevation in BCG group compared with apparently healthy group while patients control and mitomycin C groups showed insignificant elevation of IgM.
Levels of IgG showed significant elevation in patients control and mitomycin C groups compared with apparently healthy group while in BCG group showed no differences.
Serum levels of IL-10 showed no differences between apparently healthy group and each of patient's groups, also showed no differences within patient's groups Conclusions: Bladder cancer is a common urologic malignancy in male than female patients enrolled in this study.
Intravesical BCG or Mitomycin C leading to effective anti-bladder cancer immunity in the majority of Patients
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Dabbagh, Muhammad A. H.& Hasan, Jabbar S.& Abd al-Karim, Muntaha& Ata Allah, Muhammad L.. 2017. Humoral immune factor changes in group of patients with non-muscle invasive bladder cancer treated with intravesical therapy. Journal of the Faculty of Medicine Baghdad،Vol. 59, no. 4, pp.325-329.
https://search.emarefa.net/detail/BIM-809811
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Dabbagh, Muhammad A. H.…[et al.]. Humoral immune factor changes in group of patients with non-muscle invasive bladder cancer treated with intravesical therapy. Journal of the Faculty of Medicine Baghdad Vol. 59, no. 4 (2017), pp.325-329.
https://search.emarefa.net/detail/BIM-809811
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Dabbagh, Muhammad A. H.& Hasan, Jabbar S.& Abd al-Karim, Muntaha& Ata Allah, Muhammad L.. Humoral immune factor changes in group of patients with non-muscle invasive bladder cancer treated with intravesical therapy. Journal of the Faculty of Medicine Baghdad. 2017. Vol. 59, no. 4, pp.325-329.
https://search.emarefa.net/detail/BIM-809811
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 328-329
رقم السجل
BIM-809811
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر