Interleukin (IL)‎ 17 expression in Iraqi bladder carcinoma patients

الملخص EN

Intcrlcukin (IL- 17) is pro inflammatory cytokincs produccd by CD4+ T-helpcrl7 (Thl7)ccll .It has a vital cffcct on cells of the immunc systcm playing crucial rôles in pathogcncsis of immunc-mcdiatcd discascs, likc-canccrs.

The eurrent study was designed to detcct the protein expression of IL-17 in Iraqi bladder carcinoma patients, and its corrélation with clinical grades.

Tissuc samplcs were collccted from 45 patients with bladder carcinoma.

The immunoexpression of IL-17 was dctcctcd by using IL-17 monoclonal antibody.

The results of Immunohistochcmical (IHC) studying showed that tissucs with positive (IL-17) expression were low in bladder cancer patients practically in low grades with signifieant différence, it is concludcd that IL-17 expression can bc used as indicators for procession in bladder cancer.