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Correlation between vitamin D receptor gene polymorphisms and levels of some hormones in Iraqi infertile women with polycystic ovary syndrome
المؤلفون المشاركون
Abd al-Hasan, Ismail Abd al-Rida
Kazim, Sana Jasim
المصدر
Iraqi Journal of Biotechnology
العدد
المجلد 16، العدد 4 (31 ديسمبر/كانون الأول 2017)، ص ص. 104-113، 10ص.
الناشر
جامعة بغداد معهد الهندسة الوراثية و التقنيات الإحيائية للدراسات العليا
تاريخ النشر
2017-12-31
دولة النشر
العراق
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The polycystic ovary syndrome (PCOS) is a disorder that characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphologic features.
As defined by the diagnostic criteria of the National Institutes of Health (i.e., hyperandrogenism plus ovulatory dysfunction).
The purpose of this study was to investigate the correlation between VDR gene polymorphisms and level of LH, FSH, TSH and Prolactin hormones .This study was carried out in the Institute of Genetic Engineering and Biotechnology for Postgraduate Studies - University of Baghdad through the period from November 2016 - August 2017, The PCOS patients were taken from the Kamal Al-Samarraee Infertility Treatment Hospital in Baghdad.Women with PCOS (n=50) and apparently healthy control group (n=50) , were enrolled .
Genotyping of VDR gene (rs2228570) (rs7975232) , as well as (rs731236) SNPS between groups were determined by using Taqman genotyping assay .
Hormonal analysis for LH, FSH, TSH and Prolactin was performed by using Automated Immune Assay (AIA).
the results of the present study indicate that serum LH , FSH and TSH concentrations were unaffected by the studied SNPs of VDR gene within carriers of genotypes of rs2228570 , rs7975232 and rs731236 SNPs in VDR gene, while serum prolactin levels were significantly (p<0.05) higher in PCOS patients versus controls.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kazim, Sana Jasim& Abd al-Hasan, Ismail Abd al-Rida. 2017. Correlation between vitamin D receptor gene polymorphisms and levels of some hormones in Iraqi infertile women with polycystic ovary syndrome. Iraqi Journal of Biotechnology،Vol. 16, no. 4, pp.104-113.
https://search.emarefa.net/detail/BIM-811034
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kazim, Sana Jasim& Abd al-Hasan, Ismail Abd al-Rida. Correlation between vitamin D receptor gene polymorphisms and levels of some hormones in Iraqi infertile women with polycystic ovary syndrome. Iraqi Journal of Biotechnology Vol. 16, no. 4 (2017), pp.104-113.
https://search.emarefa.net/detail/BIM-811034
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kazim, Sana Jasim& Abd al-Hasan, Ismail Abd al-Rida. Correlation between vitamin D receptor gene polymorphisms and levels of some hormones in Iraqi infertile women with polycystic ovary syndrome. Iraqi Journal of Biotechnology. 2017. Vol. 16, no. 4, pp.104-113.
https://search.emarefa.net/detail/BIM-811034
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 111-113
رقم السجل
BIM-811034
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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