Synthesis and characterization of novel 1,3-oxazepin-4-ones derivatives via Schiff bases reactions with Phthalide

الملخص EN

A number of novel 1,3-oxazepin-4-ones derivatives were synthesized by acid-catalyzed cycloaddition reaction of Schiff bases with Phthalide in anhydrous THF under dry and reflux conditions with high yields.

Schiff bases were synthesized by thermal condensation reaction of aromatic aldehydes, ketones or prepared chalcones with aromatic primary amines.

The products were identified by their melting point, FT-IR, UV-Vis., 1H-NMR and 13C-NMR spectra.