Preparation and characterization of derivatives of pyrimidines in two ways clascical and microwave

الملخص EN

This study includes synthesis and characterization of new pyrimidine derivatives (R or Ar-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one), via of the reaction from cyclohexane-1,3-dione with aldehyde derivatives and guanidinehydrochlorid.

Usingabsolute ethanol as a solvent .This mixture was refluxed for (4 – 6) hrs;While maintaining the pH at 6.

The same derivatives of pyrimidine were prepared in microwave waytechnique.The prepared compounds were characterized by melting point , FT-IR , UV-Vis 1H-NMR and 13C-NMR spectroscopy