Immunomodulatory effect of Eleutherococcus senticosus on Newcastle disease vaccine in broiler

الملخص EN

The study was conducted to evaluate the effects of Eleutherococcus senticosus (ES) extract on the serum antibody response to Newcastle Disease Virus (NDV) vaccination, phagocytic index (PI) and stress index (SI) in broiler chicks.

Two hundred one-day old broiler chicks (Ross-308), were randomly divided into two main groups GA and GB (Each one 100 birds), each of GA and GB chicks were divided to 4 subgroups, 25 birds each, The 4 subgroups were symbolically named G1, G2, G3 and G4 for birds of GA, according to the three vaccination methods and control, respectively.

As well G5, G6, G7 and G8 were referred to the birds of GB.

Subgroups subjected to different methods of vaccination against ND (live attenuated Lasota strain) at 10 days-old, orally (G1&G5), oculonasal (G2&G6) and S/C (G3&G7) with killed Lasota strain, and non-vaccinated control (G4&G8).

Daily oral administration of 0.05 ml of 100% ES extract concentration/ bird, to all birds of G1, G2, G3 and G4 to the end of study.

The results of present study showed that the ES significantly increased specific antibody titer against (NDV) vaccination, increase phagocytic activity of heterophils and decrease stress index at (P <0.05).